“Demolishing anti-vaccine frauds in live debate”

Those of you lucky enough to attend Skepticon in Melbourne early last month will remember Dave Farina presenting his talk The Birth of the Science Communicator, from the USA.

He recently joined up with Dr. Dan Wilson of Debunk The Funk to take on two full time anti-vaccine grifters, Steve Kirsch and Pierre Kory. You can check out Dave’s take on how things went by dropping in on his video explanation here. Regrettably the debate turned out a predictable mess as the audience was loaded with anti-vax trolls and the conduct of the notably loathsome Kory and Kirby, meant the full schedule of discussion points wasn’t even met.

This would be because Kory, who in August last year, lost his medical licence for promoting, and wildly profiting from pushing ivermectin during COVID, spat the dummy and walked out. Aw Gosh. Anyway, there’s Gish-galloping from the anti-vax chaps and heckling from their supporters. Dave and Dan do an excellent job handling the horrific misinformation that we’re now seeing in our post COVID-19 pandemic world. I’m not surprised things went astray, as I learnt in Australia that anti-vaxxers deserve not a molecule of oxygen.

Still, perhaps given the state of anti-science rhetoric and the steady rumble of runaway grift trains, then documenting their demonstrably deceptive tactics is a pursuit with rewards we’re yet to fully appreciate. This is an almost two hour gig which is perfect for either bingeing or letting play whilst you do the housework or head out for a walk.

You can watch the same event without Dave’s commentary, at The greatest vaccine debate in history here at Pangburn. Apologies that neither video appears to permit embedding.

DNA contamination of mRNA vaccines is still not a thing

The fact that mRNA COVID-19 vaccines are not contaminated with excessive or dangerous levels of residual DNA should not really have to be addressed. Nonetheless, doing so often comes up in arguments to debunk what is becoming a persistent trope of the anti-vaccine lobby.

In November last year I looked at an excellent report from Australia’s Therapeutic Goods Administration (TGA), which plainly called the claim, misinformation. In March this year refuting the myth of “Turbo Cancer”, I went through a bunch of already well debunked attempts to justify the existence of this non-existent cancer. DNA contamination of COVID mRNA vaccines took up a few paragraphs.

The popularity of residual DNA contamination as a cause of invented harms favoured by anti-vaccine fear mongers shouldn’t surprise us. We received easy to understand information from health authorities well before the COVID vaccine rollout, that mRNA in vaccines never penetrates the cell nucleus and thus, DNA would remain untouched. Yet that very notion was targeted early and often by contrarians. Then came the flawed science with flawed methodology, that still remains unpublished. Remember the testing of vials that arrived anonymously in the mail without cold packs? Don’t forget mRNA vaccines require storage at about -20ºC. Then came sleight of hand by Kevin McKernan et al, using Qubit Fluorometric Quantification (fluorometry) in an unwarranted addition to the original testing regime of Quantitative PCR (qPCR). qPCR indicated DNA below FDA guidelines. Fluorometry significantly and inaccurately inflates results because it measures mRNA when calculating total DNA levels.

In fact there’s a few elements to understanding why DNA in mRNA vaccines is a non-event. That’s why I recommend watching Dr. Dan Wilson of Debunk the Funk on YouTube. Dan’s been flattening bogus bumps in the anti-vaccine world for quite a while now. His video on 2 July called Update on DNA contamination is one of a few he’s done tackling this particular myth. Interestingly, what recently caught my eye was Dan’s praise for the TGA report on misinformation about excessive DNA in mRNA vaccines.

Dan wrote to the TGA to check how they determine COVID DNA in their samples, as there are various ways to do this (see video 7:15). It turns out the TGA used the method that “most over-estimates the amount of DNA that could possibly be in that vial”. This still yielded “zero batches that exceeded the limit of residual DNA”.

So again, what this tells us is that DNA contamination of mRNA vaccines is a total furphy and they remain completely safe. Still, I sincerely recommend spending 10 minutes checking out Dan’s video, and having a look through his others for sound information to educate yourself about persistent and evolving anti-vaccine disinformation and misinformation.

Conspiracy Theory Attribution: An attempt to defend the Wilyman thesis

In 2015 a long standing Australian anti-vaccination activist and lobbyist, Judith Wilyman, was awarded a PhD by the University of Wollongong. Titled A Critical Analysis of The Australian Government’s Rationale for its Vaccination Policy, the work attracted exceptional criticism. I’d like to consider the veracity of certain arguments raised in defence of Wilyman’s work, noting they have arisen from one source and are themselves extensive. [Jump to Conspiracy Theory Attribution].

Antithesis

From across the globe and from multiple sources, criticism flowed readily for Wilyman’s publication. For this author, there was one thing other than the content that also rankled. The fact that it was a collection of biased references arranged to attack the integrity of one of Australia’s most effective public health initiatives. Quite striking, for a work that emerged from an academic institution, is the absence of any original research conducted by the author. As the author uses the term “thesis” we had best examine this. The Oxford dictionary offers two distinctions, with the following describing “a doctoral thesis”:

a long essay or dissertation involving personal research, written by a candidate for a university degree

This may of course seem petty unless you’ve taken time to examine this work. Nonetheless for the sake of clarity I too shall yield and refer to this diversion from genuine analysis of Australian vaccination policy, as a thesis. It is clear however, that there is no research, methodology, study, data collection or justified hypothesis. There is only a literature review and a biased one at that. Australian emergency physician Kristin Boyle describes the work as, “the inevitable product of someone with an ideology based agenda”. Genuine literature reviews that seek to examine varying or different arguments, are valuable items of research. They collate and examine related works, and in judging the strengths or weaknesses of each, offer a contention, or indeed a novel conclusion. This didn’t happen in the Wilyman literature review. Still, Judith Wilyman falsely poses herself as “an expert witness” in a family court case, a “specialist in government vaccination policies” (federal politics), and has significantly elevated her importance to the fields of vaccinology and public health.

The reality is Wilyman barely scraped in. One of her two examiners suggested the thesis was unworthy of PhD status and better suited to a Master’s degree. They observed concerns about a lack of engagement with existing literature and “the lack of an appropriate theoretical framework”. Wilyman they argued, had conducted no original research nor contributed to the knowledge of the subject. This conflict was resolved by the rare event of appointing a third examiner. Australian Skeptics Inc. report (archived):

That third examiner, also unnamed, judged that, while the thesis as assessed showed Wilyman conducted original research, it did not make a significant contribution to knowledge of the subject, had no indication of a broad understanding of the discipline within which the work was conducted, and that it was not suitable for publication. 

They recommended that the thesis be resubmitted, and gave “extensive and detailed comments on areas that need to be improved”, sharing the same concerns as the earlier critical examiner.

This revised version was consulted by only one examiner; the third individual who had requested the significant changes. The original “earlier critical examiner” was not asked for an opinion. The examiner who had accepted the original, doubly-rejected thesis, was considered a certainty for the improved version. Thus, a year later than she planned, Wilyman had her PhD.

In the excellent article, PhD thesis opposing immunisation: Failure of academic rigour with real-world consequences (Vaccine 37; p. 1542), Wiley et al postulate as to how this oversight possibly came to be:

The quality of the writing and presentation of the thesis is such that many of its arguments could seem plausible to an examiner without specific content knowledge, despite sound academic credentials. Our combined expertise (vaccinology, epidemiology, the history and practise of immunisation policy development globally and in Australia, social science) and as PhD examiners, both gives us detailed knowledge of the sources cited by the thesis, and allows us to identify key deficiencies […] A critical analysis should consider the merits and faults of an issue and be conducted in a way that is not designed to find only evidence for the writer’s pre-determined conclusions. […] This thesis does not include methods for assessing the literature, does not discuss aspects of identified studies which may contradict one another, or attempt to establish the quality of relevant studies. Rather, the references used are highly selective, only citing a small number of the available epidemiological studies and clinical trial reports, all of which are interpreted to support conclusions which appear pre-determined.

The Supervisor

A News GP summary of the above paper in Vaccine is available here. Let’s examine the first sentence in the above quote. Firstly, does it help us understand how such a deliberate failure to include material supporting Australia’s vaccination policy was not addressed by Wilyman’s supervisor? Secondly, is it likely such a biased collection of arguments was missed because examiners, and particularly the supervisor, lacked “specific content knowledge”? Sure, Wilyman studied within the School of Humanities and Social Inquiry. Her supervisor, Professor Brian Martin completed his PhD in Theoretical Physics and later became a Professor of Social Sciences, at the University of Wollongong. But not being qualified in vaccinology, related fields or policy development does not render senior academics incapable of accessing evidence or seeking consultation. More so, Wilyman’s published acknowledgement of her supervisor is unambiguous;

I would also like to thank Professor Brian Martin, my primary supervisor at the University of Wollongong, for his unwavering support and encouragement. His weekly phone calls kept me focused and there were many robust discussions that helped me to overcome the significant opposition to this project. I thank him for his patience and dedication to my research.

It’s important to acknowledge that the role of Professor Brian Martin (left) in Wilyman’s thesis was not just one of “unwavering support” for her many unsupported claims, but one in which his own later accounts afford academic freedom more importance than academic integrity. I shall endeavour to be as fair as possible in referencing claims Brian Martin has made in defence of the Wilyman thesis. I will seriously consider the notion of Conspiracy Theory Attribution (CTA) and the suggested failure of critics to analyse the thesis and citations presented.

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“I didn’t know that”: RFK Jr. offers genuine insight

As US Secretary of Health and Human Services, Robert F. Kennedy Jr. has overseen financial and staffing cuts to infectious disease, mental health and addiction services. However, he appears to be unaware of this and the extent of the harm he has caused.

In trying to ascertain exactly where his head is at, consider his visit to the unvaccinated Mennonite community in Seminole, Texas, where a measles epidemic rages, killing children and nearly killing others. Kennedy posted on X about his visit with a couple whose 2 year old daughter was discharged after 3 weeks in Intensive Care. He also offered:

I also visited with these two extraordinary healers, Dr. Richard Bartlett and Dr. Ben Edwards who have treated and healed some 300 measles-stricken Mennonite children using aerosolised budesonide and clarithromycin.

Healed? Really?

Well, no. Nothing “heals” measles. There is no cure. Richard Bartlett has previously claimed budesonide was a miracle cure for COVID-19. His extensive research involved being asleep during which time “an answer to a prayer” came to him. With patent laws on divine intervention being sketchy at best, it’s no surprise that this is now a cure for measles. So, what is aerosolized budesonide when it’s at home? A bronchodilator, often simply called an asthma inhaler, after its most common use. As noted in the video below, Dr. Paul Offit warns of the immune inhibiting qualities of steroids like budesonide and the obvious danger this poses during measles infection.

The other “extraordinary healer”, Ben Edwards, has recently volunteered that mass infection is “God’s version of measles immunisation”. This guy is peddling prayer and unproven treatments whilst wandering about his so-called clinic, himself infected with measles. When devotees from the Kennedy-founded anti-vaccine lobbyist group, Children’s Health Defense praise him for his negligence he offers, “I’m only doing what any good doctor should be doing”.

So here we are, now getting an idea of how US public health initiatives unfold under Kennedy. I wonder if this is what Trump had in mind when he said “Go wild Bobby”. To make the whole thing even more bizarre is the fact other anti-vaccine identities are criticising Kennedy for observing, tucked at the bottom of another post on X, that the MMR vaccine is “the most effective way to prevent the spread of measles”. They may be happier with the falsehoods he has since announced about “treating” measles (you can’t) that cases are inevitable because the vaccine “wanes very quickly” (it doesn’t), and 14 studies not linking autism to vaccines are “invalid” (no evidence provided) .

With her apt tone, Rachel Maddow runs through a few of Kennedy’s recent failures, in the MSNBC video below…

Turbo Cancer: Time for this anti-vaccine myth to die

“Turbo cancer” does not exist. Oncologists reject the notion entirely. Aside from the ridiculous name, there is no evidence to support it. Bold claims promoting it as fact, are not merely invalid, but scientifically incompetent. Proponents offer no clear definition, other than insist DNA can be damaged by COVID-19 vaccines, leading to aggressive cancers. As the “died suddenly” trend begins to die out, “turbo cancer” is in top gear.

We’re told residual DNA in vaccines is responsible. Or, the vaccines enter the cell nucleus. Or, it’s not a vaccine – it’s gene therapy. Or, simian virus 40 (SV40) is the cancer-causing agent in mRNA vaccines. This last claim has origins reaching back to the 1950s and 1960s when discovery of SV40 present in oral polio vaccine was responsible for safety concerns and later cancer fear-mongering. Mechanisms of infection were verified as possible but rare, and allegations of a surge in cancers decades later, are unverified. SV40 was one of the first oncogenic viruses discovered. These viruses cause cancers in experimental animals and in some cases humans. However, not in this case. When it comes to COVID-19 vaccines, some mRNA preparations may contain SV40 fragments, which aren’t the same as the virus and are not carcinogenic. In fact there is no evidence of this ever having occurred. The fragments occur because part of SV40’s DNA sequence is used in the beginning of mRNA vaccine development.

As for so-called “turbo cancer” [Wikipedia] the term has its origins at least as far back as November 2020, according to the indefatigable Orac, who identified it in a smarmy comment to a forum post about Moderna’s request for clearance of its mRNA vaccine. By November 2022, use of the term had spiked online. It was being promoted and amplified by a number of anti-vaccine activists on social media. One such group was RFK Jr.’s Children’s Health Defense (CHD) which had emerged as a major distributer of COVID disinformation during the pandemic. In January 2023 AFP fact-checked a November 2022 Rumble video produced by CHD, featuring disgraced Canadian doctors Charles Hoffe and Stephen Malthouse. AFP reported that oncologists had informed them the claims were baseless, and added:

“There is no evidence in Canada or globally that vaccination leads to any forms of cancer or that Covid vaccines lead to rapid advancement in cancers,” British Columbia’s Ministry of Health said in a statement emailed January 11. “There is also no evidence to support Covid vaccines leading to harm to the immune system; on the contrary evidence strongly supports that Covid vaccines produce strong, effective immune responses that protect from serious illness from SARS CoV-2.”

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