Category Archives: Human Rights

The awful autism obsession of the antivaccinationist

Posted in General, Health, Human Rights, Legal, Scam by

On page 11 of the most recent Health Care Complaints Commission investigation into the Australian Vaccination-Skeptics Network, we see the absurdity of vaccines causing autism rearing its head.

The AVSN claim to present on their website 68 “medical journal studies [that] support the link between vaccination and autism”. According to the HCCC the expert they consulted concluded a case of correlation confused as causation was evident. A read of the list shows the expert is being kind in no small part. Given that the AVSN claim these studies show a link between vaccines and autism, the list is quite absurd.

Despite the absence of mercury in childhood vaccines we get much on environmental mercury and autism, ADHD and blood mercury levels, swollen brains and autism, etc. But we have a numeric problem Houston. Of the 68 (cough) articles, I could count just 30 that included the word “vaccine” or “vaccination” in the title, abstract or conclusion. But maybe I’m expecting too much. Articles are numbered but items 5, 12, 48, 49 and 68 don’t exist. At all.

The AVSN use the typical misinformation that succeeds at confusing young worried parents and educated, affluent parents who can afford lots of Internet time. Such as citing the damage huge doses of certain toxins or heavy metals can do, without stressing vaccines contain either another variant or minuscule amounts long shown to be perfectly safe. Since having changed their byline from Love them, Protect them, Never inject them to Because every issue has two sides, they have done a poor job of presenting both sides.

The AVSN for example do not provide access to the Institute Of Medicine publication, Adverse Effects Of Vaccines; Evidence and Causality. This has been pointed out by the HCCC along with a host of biased schemes the AVSN execute in the hope of driving the public away from vaccination. In addition the hubris-riddled response that has been crafted for the HCCC and published online, is indicative of a mindset with no concept of community responsibility.

Myths and concerns about vaccination note on page 29 under “Mercury in vaccines can cause autism”:

There is no evidence that thiomersal (a mercury based preservative) in vaccines has caused any health problems, except perhaps minor reactions such as redness at the injection site. […] The form of organic mercury contained within thiomersal is “ethyl mercury” which doesn’t accumulate in the body, unlike the closely related methyl mercury which does accumulate and is neurotoxic. […] MMR vaccine and other live attenuated viral vaccines never contained thiomersal.

Of course there is a dollar to be made insisting vaccines cause autism and other disabilities. As reported recently by Fairfax:

The Office of Liquor Gaming and Racing has confirmed it is investigating ”problems” in the Australian Vaccination-Skeptics Network’s financial statements.
The anti-vaccine group has raised nearly $2 million in the past seven years but has never done any ”charity”, according to Stop the AVN, a coalition of critics formed after the parents of a baby who died of whooping cough were targeted by the network. […]

The 2008 financial statement said the group had more than $50,500 of assets, yet in its 2009 statement, assets from 2008 are listed as only about half that amount.
And nearly two-thirds of $281,855 in expenses listed on its 2010 financial statements are not explained, given only the title ”other expenses”. The 2012 statement for the group has not been submitted.
A chartered accountant who examined the documents for Fairfax Media, but declined to be named for fear he would be harassed, said the documents were ”the worst set of financial statements I have ever seen”.

$2 million! And where is that money? Well, you see… no-one really knows. A visit to this document reveals a copious tally of financial irregularities and charitable breaches by the (then) AVN. Both the Charitable Fundraising and Charitable Trusts Acts are called into question, “on a number of occasions” according to the NSW state watchdog, the OLGR.

Published just recently at Diluted Thinking the article, AVSN Pays Meryl Dorey is a must read. It is a thorough breakdown of financial irregularities and unanswered questions from 2004 to 2008.

It is of course beyond ironic that a hero of the AVSN is disgraced “vaccine/autism” fraudster, Andrew Wakefield. It’s old news that Brian Deer was able to track Andrew Wakefield’s scam because the latter had left a trail of intriguing financial records and/or references.

Follow the money was what Deer did in true investigative journalistic style. It is indeed somewhat silly that the anti-vaccine lobby today bellow follow the money, but in doing so can draw only one step from a vaccine to its manufacturer. The money trail Deer uncovered was far more impressive.

Wakefield was paid £150 plus expenses per hour by Richard Barr’s law firm. In total this came to £435 643, which was arguably to create a syndrome to drive the class action of anti-vaccine and genuinely misled (by Wakefield) litigants.

But Wakefield needed to ensure he profited from all the sufferers of his syndrome. Once the world had been fooled into believing “autistic enterocolitis” was a genuine syndrome, then it would have to be diagnosed. First he filed for his March 1995 Diagnostic patent that claimed in part:

Crohn’s disease or ulcerative colitis may be diagnosed by detecting measles virus in bowel tissue, bowel products or body fluids

Based on this, on September 9th 1996 a client of Richard Barr known as Child 2 was the first child subject to what the GMC later described as a “clinically unwarranted” ileocolonoscopy.

The day after Child 2 had undergone his ileocolonoscopy Wakefield produced a document headed, Inventor/school/investor meeting 1. 4 which calculated that by working on MMR litigant samples, profits of £72.5m per year were to be had. This document left no doubt as to from where the money should be sourced. The profits would go to a yet to be formed company specialising in molecular viral diagnostic tests:

In view of the unique services offered by the Company and its technology, particularly for the molecular diagnostic, the assays can command premium prices. The ability of the Company to commercialise its candidate products depends upon the extent to which reimbursement for the cost of such products will be available from government health administration authorities, private health providers and, in the context of the molecular diagnostic, the Legal Aid Board.

More could be gleaned from a confidential submission (1999) to the Legal Aid board in his quest to secure the future of an immunodiagnostic business he would be director of. Unigenetics Ltd was incorporated in February of that year with Dublin pathologist, John O’Leary and would be registered in the Republic of Ireland. Here Wakefield argued the link b/w MMR and autism had been shown. Unigenetics scored £800 000 of tax payer funds to conduct PCR tests of dubious pursuit.

In addition to these petty “legal costs and salary” monies Wakefield would get another £90 000 per year – more than half of which was for travel. Deer reported that trading was to be fronted by another planned immunodiagnostic company Carmel Healthcare Ltd (also registered in the Irish Republic) and named after Wakefield’s wife. Within this venture Wakefield would take 37% of the earnings, the parent of child “Number 10″ would take 22.2%. A venture capitalist would get 18%. Royal Free’s professor of gastroenterology, Roy Pounder would get 11.7% and Professor John O’Leary another champion of “MMR causes autism” would get 11.1%.

Deer was given a copy of a prospectus 35 pages long.

This included confirmation of planned “litigation driven testing” from the USA and UK, along with delightful profit. Of course all business relied upon Wakefield’s new syndrome which at this point remained to be proven. As he had not found Crohn’s disease in the 12 children, Wakefield coined the term “autistic enterocolitis”. The prospectus sought to raise an investment of £700 000.

It is estimated that the initial market for the diagnostic will be litigation driven testing of patients with autistic enterocolitis from both the UK and the USA… It is estimated that by year 3, income from this testing could be about £3 300 000 rising to about £28 000 000 as diagnostic testing in support of therapeutic regimes come on stream.

[…]

Once the work of Professor O’Leary and Dr Wakefield is published, either late in 1999 or early in 2000, which will provide unequivocal evidence for the presence of the vaccine derived measles virus in biopsy samples the public and political pressure for a thorough, wide ranging investigation into the aetiology of the bowel conditions will be overwhelming.

As a consequence of the public, political and legal pressures brought to bear, the demand for a diagnostic able to discriminate between wild type and vaccine derived measles strains will be enormous.

Deer reported on yet another new company which was for the running of a joint business with the UCL medical school. Immunospecifics Biotechnologies Ltd would produce immunotherapeutics, vaccines and a diagnostic test. Beneficiaries were as with Carmel. Wakefield, the parent of “number 10”, the venture capatilist, Pounder and Prof. John O’Leary.

There are issues around Wakefield’s immunodiagnostics which antivaccinationists should simply admit, and by not admitting such merely lend their cause less credence (if that were possible).

  • Transfer factor for use in vaccines and treatments had basically been written out of the literature. A lack of evidence, risk of infection and unjustified cost had relegated this 1940’s blood product to the realm of an Internet peddled cure-all scam.
  • The Neuro Immuno Therapeutics drama run by Hugh Fudenberg. To cure autism – which he reckons is caused by MMR – Hugh would use, you guessed it, Transfer factor. In August 2004 Brian Deer caught up with him. At the time he was under sanction for use and prescription of controlled drugs. Help yourself to a search-and-read on Hugh. If you remember Bill Maher’s claim that a flu shot five years consecutively equals a ten-fold increase in the chances of developing Alzheimers, you might be relieved to know that the source is Hugh Fudenberg.
  • The Dublin measles tests which could not deliver consistency of results, emerged as a problem years later, during vaccine related lawsuits in the USA and Britain.

One caper of Wakefields that many know of is his “safer vaccine” patent for a monovalent measles vaccine. As the Royal Free Hospital approached the release of his paper Wakefield made copies on tape as to how he should announce his bogus findings. One – which is in circulation today – includes:

There is sufficient anxiety in my own mind for the long term safety of the polyvalent vaccine—that is, the MMR vaccination in combination—that I think it should be suspended in favour of the single vaccines

But of course! Just as well that like the patent for immunodiagnostics he had the “safer vaccine” patent for the single measles vaccine. And he filed for this nine months before his now retracted paper was published.

Wakefield patent

The opening paragraph is breathtaking:

The present invention relates to a new vaccine for the elimination of MMR and measles virus and to a pharmaceutical or therapeutic composition for the treatment of IBD (Inflammatory Bowel Disease); particularly Crohn’s disease and Ulcerative Colitis and Regressive Behavioural Disease (RBD).

After falsely claiming MMR vaccination leads to Crohn’s disease and other forms of IBD we read on page two (far right) above (bold mine):

What is needed therefore is a safer vaccine which does not give rise to these problems and a treatment for those with existing IBD. I have now discovered a combined vaccine/therapeutic agent which is not only most probably safer to administer to neonates and others by way of vaccination, but which also can be used to treat IBD whether as a complete cure or to alleviate symptoms.

This was first revealed in the UK Sunday Times. Wakefield denied this “conspiracy”:

The claim appears to be that, whilst at the Royal Free Hospital, I was developing a new vaccine to compete with MMR and that I conspired to undermine confidence in MMR vaccine in order to promote this new vaccine, and that this represented a conflict of interest. This is untrue. The facts are that: […]

it has never been my aim or intention to design, produce or promote a vaccine to compete with MMR; […]

A provisional patent filing was made for the use of measles virus-specific TF in regressive autism and inflammatory bowel disease (Regressive Bowel Disease; RBD).

The reference to the possible use of TF to protect children against measles infection – the thrust of the Sunday Times’ conspiracy theory – was put in as an afterthought in the patent. It was entirely speculative and never pursued in any shape, manner or form.

The provisional patent filing was entirely speculative and was for a possible therapy; as such, it had no bearing on the 1998 Lancet paper.

That the patent application with its firm conclusion of an MMR derived pathology appeared nine months before publication of his paper is not the only Crystal Ball caper by Wakefield. A fortnight before selecting any children that eventually made up his insignificant 12 child sample, Wakefield and Richard Barr co-authored a letter that included (bold mine):

Children with enteritis and disintegrative disorder, form part of a new syndrome. The evidence is undeniably in favour of a specific vaccine induced pathology

That claim would have taken the word of Hugh Fudenberg at that particular time in history.

The end for Wakefield came just after plans for Carmel Healthcare were finalised, potentially making way for his incredibly profitable business. A new head of medicine, Mark Pepys was appointed to the UCL Medical School (once known as the Royal Free and University College Medical School). He is a fellow of the Royal Society and ensured impressive grant money. He wasn’t impressed by Wakefield, threatening to not transfer his own unit to UCL if Wakefield was even there.

With the help of theoretical physicist Chris Llewellyn-Smith he made his move in December 1999. A mere two months after Pepys moved to the Royal Free Wakefield was called to UCL’s London head offices. There, at last, he was made to face the audacity of his scam and handed a two page letter of his very own to have and to hold and of course, to read. It included:

We remain concerned about a possible serious conflict of interest between your academic employment by UCL, and your involvement with Carmel. This concern arose originally because the company’s business plan appears to depend on premature, scientifically unjustified publication of results, which do not conform to the rigorous academic and scientific standards that are generally expected. […]

Good scientific practice now demands that you and others seek to confirm or refute robustly, reliably, and above all reproducibly, the possible causal relationships between MMR vaccination and autism/“autistic enterocolitis”/inflammatory bowel disease that you have postulated.

Yay verily.

UCL were keen to help, offering him an ongoing position on staff or a full twelve months paid absence to allow for further research. 150 subjects would be provided to Wakefield. 12.5 times larger than his initial sample. Wakefield agreed.

Time passed.

After three months he was asked for a progress report. Six months later in September 2000 Wakefield replied:

It is clear that academic freedom is essential, and cannot be traded. It is the unanimous decision of my collaborators and co-workers that it is only appropriate that we define our research objectives, we enact the studies as appropriately reviewed and approved, and we decide as and when we deem the work suitable for submission for peer review.

Fail. By October of 2001 he was asked not to let the door hit his lying backside on the way out. In January of 2010 the General Medical Council found Wakefield had been “dishonest, irresponsibile and showed callous disregard for the distress and pain of children.”  [Science Based Medicine]

After close to a decade of multiple studies had failed to replicate his “findings” or any link between MMR, its components and autism the Lancet retracted the Wakefield paper [Science Based Medicine] [BMJ] on February 2nd 2010. The journal’s editor, Richard Horton described the statements in the “fatally flawed” paper as “utterly false”.

On May 25th of that year he was struck off the medical registrar by the General Medical Council.

Still today, as is clear above, there are scam artists profitting from peddling the lie that vaccines cause autism. Their paper-thin efforts may well be pathetic but still have a measurably negative effect on public health. With no regard for evidence or responsibility for the consequences of their actions, one can hope that these arrogant fraudsters will one day too face the weight of the law.

Yay verily.

Vaccines contain no aborted fetal cells

Posted in Anti-Vaccination Lobby, Chiropractic, Health, Human Rights, Legal, Religion by

One of the most offensive lies peddled about vaccines is that they “contain aborted foetal cells”.

Consider this April 2013 screenshot from AVN Facebook:

Aborted fetal tissue

I noticed an even more absurd take when reading Anti-vaccine chiropractors redux-1, c/o reasonablehank. He was reviewing the anti-vaccine rantings of one “Dr” Koe Davidson who is a chiropractor running Peak Potential Health and Wellness in Mentone, Melbourne. One screenshot includes Davidson addressing vaccine ingredients as listed by the CDC. It includes:

Oh and “egg protein” = fancy word for aborted fetus cells. This wording was changed in mid 2012… Scary stuff.

For a document last updated in February 2012 I’m not sure what he’s trying to convey. The CDC cannot have changed egg protein to aborted “fetus” cells in 2012 as this would be complete nonsense. Thus one must conclude he is either utterly confused on the topic of cell cultures or – as is common with chiropractors aligned with the CAA – misinforming readers.

The CDC write about egg protein as a vaccine additive:

Egg protein is found in yellow fever and most influenza vaccines, which are prepared using chicken eggs. Ordinarily, persons who are able to eat eggs or egg products safely can receive these vaccines.

So how can such confusion on cell cultures come to pass? Today strains of human diploid cell culture are grown in containers in laboratories. In the manufacture of vaccines, viruses that infect humans are grown in these human diploid cell lines. One strain of human diploid cell culture was made in the USA in 1961. Labelled WI-38 this strain came from the lung tissue of an aborted female of three months gestation.

Another human diploid cell culture was produced in the UK in 1966. The tissue came from the lungs of a 14 week old male foetus and the strain is labelled MRC-5. W.I. refers to the Wistar Institute. M.R.C. refers to the Medical Research Council.

The abortions did not take place with the intent of producing human diploid cell culture for use in vaccine manufacture. The biologists who produced the diploid cultures did not induce the abortions. Both abortions were intentional and would have been carried out whether the foetal tissue had that fate or not, post abortion.

These cells used to grow viruses have been reproducing since 1961 (WI-38) and 1966 (MRC-5), respectively. The viruses produced this way are further processed and sterilised in the production of the vaccine. In this way any potential for contamination with foetal material is eliminated. Furthermore, strict quality control measures are employed to examine each vaccine to ensure no foetal material is present.

♣ The USA National Network for Immunization Information state (bold mine):

These two cell strains have been growing under laboratory conditions for more than 35 years. The cells are merely the biological system in which the viruses are grown. These cell strains do not and cannot form a complete organism and do not constitute a potential human being. The cells reproduce themselves, so there is no need to abort additional fetuses to sustain the culture supply. Viruses are collected from the diploid cell cultures and then processed further to produce the vaccine itself. ♣

Vaccines produced using WI-38 and MRC-5 human diploid cell lines include hepatitis A, rabies, rubella, MMR, varicella and Pentacell DTaP-IPV/Hib.

Another abortion was performed on a rubella virus-infected mother in 1968. Both mother and foetus were infected with wild rubella and this posed the risk of major birth defects. Foetal tissues were obtained and wild rubella virus (RA27/3) was isolated. This has been grown in human foetal diploid cell line WI-38. No foetal tissue is present in the vaccine. No further abortions are necessary to produce more vaccines.

Prior to isolation of RA27/3 the USA experienced 800 cases of congenital rubella annually. At the turn of the century only three babies with congenital rubella were born. Research was carried out to study the possibility of using other animal cells to produce the RA27/3 rubella vaccine. However these proved less effective and less safe.

The Vatican accepts the use of human diploid cells in the manufacture of vaccines. A June 9th 2005 Vatican City Statement on Aborted Fetal Vaccines acknowledges this. It notes use of these cell lines is:

…to avoid a serious risk not only for one’s own children but also, and more specifically, for the health conditions of the population as a whole – especially for pregnant women.

For example, the severe epidemic of German measles which affected a huge part of the United States in 1964 thus caused 20,000 cases of congenital rubella2, resulting in 11,250 abortions (spontaneous or surgical), 2,100 neonatal deaths, 11,600 cases of deafness, 3,580 cases of blindness, 1,800 cases of mental retardation. It was this epidemic that pushed for the development and introduction on the market of an effective vaccine against rubella, thus permitting an effective prophylaxis against this infection.

[And observes that]

…the parents who did not accept the vaccination of their own children become responsible for the malformations [due to rubella infection] in question, and for the subsequent abortion of fetuses, when they have been discovered to be malformed.

Think of an apple orchard. The organic material nourishing the trees includes (say) manure, bird droppings, animal carcases, rotting vegetation and so on. If one eats an apple one is not eating manure or the carcass of an unfortunate passing mammal. To say vaccines contain cellular material is to employ exactly such flawed thinking.

A vaccine initially made using human diploid cells that passed FDA requirements via another production method is the RabAvert rabies vaccine by Chiron Corporation. When safe and effective alternatives can replace the methodology involving human diploid cells we shall begin to see them. It is a fact that the human strains are superior in many ways. However they are not, in any way shape or form, “aborted foetal cells”.

The claim that vaccines contain the cells of aborted foetuses or are contaminated with any organic material is quite simply false.

Every Vaccine Is A Little Victory

Posted in Anti-Vaccination Lobby, Health, Human Rights, Science by

Vaccination is now recognised as one of the most successful and effective public health interventions for saving lives and promoting good health.
Prevention is a key goal in healthcare and the ability of vaccines to prevent illness and death associated with many serious diseases is one of the success stories of scientific innovation

♦♦ Dr. James Reilly, Minister for Health, Ireland ♦♦
Still from "vaccination victory" video

Last month, during European Immunisation Week (April 21st – April 27th), Ireland launched a rather clever campaign to help remind the public of how crucial national immunisation programmes are. More importantly it included how vital it is to complete a vaccine schedule. A schedule may be one or a varied series of vaccinations, immunisations, shots and/or doses.

These may be had once, twice, three or even more times, at different ages, when exact or different time-periods have elapsed, and at which the same or different amounts of vaccine is given. Boosters can be scheduled or even recommended for other members of the family. All this depends almost exclusively on the vaccine under consideration.

So it seems that the development of immunity is remarkably complex. It is not difficult but it’s complexity can be gleaned through the above and use of terms such as “partial immunity”, “fully immune”, “waning immunity”, “herd immunity”, etc. Thus it’s very important to take the advice of your GP, doctor or local health authority rather than try to “research” the topic yourself.

The development of immunity may be complex, but we do know the development of vaccines is perhaps the greatest advance of modern medicine. In fact rather than getting bogged down in the copious amount of information regarding vaccines one could simply observe that Every Vaccine is a Little Victory.

Which brings us to the campaign itself launched last month in Ireland. Check out the video below. Chaps: you’re permitted to chuckle, smile, use words like “cool”, “nice kid”, suggest it’s a “top idea” and so on. Ladies: you may “Squeeee!, use words like “cute”, “gorgeous”, “Awwwwww”, etcetera. Do pass it around, all.

No matter how you react I trust you agree it’s a good idea. There is so much information and misinformation about vaccination, that purporting to “research” the topic and decide against vaccination is likely to involve denial of evidence. Indeed, quite a lot of evidence denial goes into rejecting vaccination.

Similarly, it’s going to prove rather challenging to suavely explain to ones mates and relatives the immunodynamics behind ones child’s third MMR vaccine. One might also look overly ambitious mounting a dinner discussion based on why it is quite safe to “complete the MMR schedule, chaps, in temporal proximity to this seasons influenza vaccine”. 

Or reassure the gang over coffee that Janine can have faith in the immunogenicity of the live-attenuated influenza vaccine (LAIV) taken concurrently with the twins’ 56 week MMR dose. Perhaps, what’s really on everybody’s mind is the GMP standards as they apply to the reconstitution of vaccine diluent preparations?

Umm… No. As stated the amount of information out there is truly copious. Only the anti-vaccine lobby can keep a straight face whilst claiming to grasp the entirety of vaccine science and rewrite it’s conclusions at the same time. Perhaps they have drastic inside information on reconstituting vaccine diluent preparations?! Or rather, perhaps their unique way of getting attention is just a unique way of… getting attention.

For the rest of us, given that it’s far better to accept the word of qualified experts who overwhelmingly support vaccination, the word on the street is that Every Vaccine is a Little Victory. Presently it’s vital to remember this. The South of Wales in the UK is in the grip of a measles epidemic. Well over 1,100 cases and a frantic MMR catch-up programme has left the anti-vaccination lobby with all the charm of a malignant Chucky the Court Jester.

Australia has been fighting unacceptably high pertussis levels for years now. Recently, Aussie health authorities have begun to act on inadequate legislation that has well served the deceptively named Australian Vaccination Network Inc. Concurrently the AVN Inc. are fighting the NSW Office of Fair Trading to keep the name that has led to so much sickness, deception and despair.

With rising conscientious objection in the developed world, vaccine preventable diseases once thought all but eradicated are making a firm comeback. In the developing world, communities and parents are risking their lives to access vaccines for their children.

It was with certain purpose last month in Dublin then that Dr. James Reilly the Irish Minister for Health addressed a crowd gathered at the Royal College of Physicians, Trinity College. Health News Ireland reported that, Reilly observed:

“Vaccination is now recognised as one of the most successful and effective public health interventions for saving lives and promoting good health,” he told the gathering in the prestigious Royal College of Physicians, which nestles in the shadow of Trinity College.

“Prevention is a key goal in healthcare and the ability of vaccines to prevent illness and death associated with many serious diseases is one of the success stories of scientific innovation”.

He appeared to have no time for the detractors, the nay-sayers; or the ‘scattered thinking’ brigade, as he dubbed them.

Every vaccination is a little victory

Modern humans do poorly at gauging risk-benefit. A Pfizer booklet titled Vaccines – Protect Your Health at Every Age includes:

The vast majority of side-effects are minor and temporary, such as a sore arm or mild fever and have nothing to do with the infectious disease against which the immunisation is directed. New vaccines go through a rigorous testing in development and approval phases in Europe to make sure they are safe. The European Medicines Agency also monitors any adverse side-effects that might occur after the medicine is licensed.

In Ireland the National Immunisation Advisory Committee advises the “Chief Medical Officer in the Department of Health on immunisation-related and vaccine matters”. Their responsibility to the Department of Health is to ensure the ability “to enable evidence-based immunisation related policy decisions”.

Committee Chair is Professor Denis Gill – (interviewed here). He ponders vaccines as a victim of their own success.

A lot of parents don’t realise just how bad the past was. Take measles, for instance: 1-in-1,000 children will die as a result of contracting measles.

Put it another way, one of the reasons we are living longer is because we are surviving childhood.

It is of course, beyond ironic. This theme arises in other areas also – from human rights to consumer rights.

Our health and longevity afford us the opportunity, through ignorance, to sabotage the very means that provide the improvements in the first place.

Every Vaccine Is A Little Victory

——————

GAVI Alliance: the success continues

Posted in Anti-Vaccination Lobby, Health, Human Rights, Science by

One of the most impressive speakers I’ve had the pleasure of hearing is Seth Berkley.

Seth is CEO of the GAVI Alliance. The incredible life-saving machine known as “the GAVI model” has prevented over 5 1/2 million future deaths through the immunisation of 370* million children since 2000.

* – May 2012 projection

GAVI’s mission encompasses a bold, compassionate vision, effective strategies, education and commitment. GAVI has pulled together very specific dynamics of international development, finance organisations, donor governments, the pharmaceutical industry, developing countries, WHO, UNICEF, Bill and Melinda Gates Foundation and the World Bank into a single “decision-making body”.

This uniquely complex approach allows the central part of the GAVI vision to be realised:

Saving children’s lives and protecting people’s health by increasing access to immunisation in poor countries

GAVI has every right to be proud that its model has permitted “a single-minded focus to the urgent task of closing three critical gaps in the provision of vaccines”:

  • between children for whom immunisation is a given and the 19 million children worldwide with no access to vaccines;
  • between the introduction of a new vaccine in rich countries and the average 10-15 years required for the same vaccine to reach low-income countries;
  • between the need for new vaccines in developing countries and the lack of research and funds to provide them.

In 2009 UNICEF reported that more children are being immunised than ever before and this is “directly attributable” to the success of the GAVI model. With the support of GAVI, 18 developing nations had begun to introduce the pneumococcal vaccine by mid-2012. Better still this vaccine will soon be part of routine programmes in half of GAVI-eligible countries. Pneumonia is the cause of 18% of child deaths in developing nations.

Another 18% of deaths in children is due to diarrhoea, primarily caused by rotavirus. By the end of last year 20 GAVI-eligible countries had been approved for support in implementing vaccines against rotavirus. It’s wonderful that by the end of last month Sudan was joined by Rwanda, Malawi and Ghana as the first African nations to see GAVI help roll out rotavirus vaccines.

Consider for a moment, Ghana. The first GAVI supported country to introduce both rotavirus and pneumococcal vaccines together, Ghana can now directly address and prevent the cause of 36% of childhood fatality.

GAVI have excelled in meeting demand. In the middle of 2011 more applications than ever before were made to GAVI for both new and underused vaccines. Late last year two thirds of GAVI programmes met demand for both rotavirus vaccine (representing a nine fold increase) and pneumococcal (representing a doubling of demand). The diagram below indicates how GAVI commits funds to specific purposes.

Meanwhile in the developed world we continue to enjoy the luxury of faux “vaccine injuries” and other hoax reasons proffered as cause to deny children immunisation. This itself is an indicator of, and direct result from, the success of mass immunisation. Vaccine induced immunity and herd immunity protecting the unvaccinated, remains out of reach in poorer nations wherein one child dies from a vaccine preventable disease every 20 seconds.

Where vaccination regimes have been successful such tragic suffering is forgotten. Indeed, subtracting the impact of vaccine denial, there’s virtually no evidence of it in our midst. But this does not mean we may have cause for complacency – no matter how strong both specific and herd immunity might be. Influenza pandemics remain a serious threat to humanity. It’s been estimated that the likelihood of such a Massively Fatal Discontinuity, able to kill up to 100 million people in the next 50 years, is 100%.

Back in February 2010 Seth Berkley looked at the importance of vaccines to human health, and our survival.

Wise words.

HIV and flu — the vaccine strategy (TED Talks)

Source – GAVI

Naltrexone implants backed by zealotry but not evidence

Posted in Anti-Drug Lobby, Health, Human Rights, Illicit Drug Policy, Science by

Less than a month after Sydney coroner Mary Jerrum referred a provider of naltrexone implants to the NSW Health Care Complaints Commission, the Christian Democrats’ Reverend Fred Nile revealed he wants them used as compulsory treatment for opioid addicts.

Naltrexone implants are not backed by any convincing evidence but the rapid opioid detoxification [ROD], opioid blocking properties they offer appeal greatly to anti-drug crusading Christian evangelists. Long opposed to harm reduction measures and evidence based treatment of addiction, such as methadone maintenance, far right Christians and conservatives see naltrexone implants as a moral masterstroke. Muscling into the action in recent years are the profit-focused, such as Sydney’s Ross Colquhoun, director of Psych ‘n’ Soul.

I’ve previously written about Dr. Stuart Reece, who features in the video below with the same title as this post. His abuse of patients with naltrexone and Jesus saw 25 of them die in 20 months. His career is the epitome of callous faith based pseudoscience which uniquely targets evidence based harm reduction measures. When I posted on a faux “research” paper he had co-authored with other members of Drug Free Australia, I referred to an exchange on an email list hosted by the Alcohol and Drug Council of Australia. It was on this list years ago that I first read Ross Colquhoun defend naltrexone implants as “common sense”. Indeed his evidence free defence of implants led me to conclude that his “common sense” was the equivalent of the religious zealots’ “belief”.

Both individuals are signatories to Drug Free Australia’s so-called position statement which includes funding of naltrexone implants as an “urgent pro-active change to our illicit drug policies”.

DFAposition_statement_sigs1

Handing down scathing findings into three deaths, the coroner recommended that the HCCC consider proceedings against a doctor working at Colquhoun’s Pysch ‘n’ Soul, Dr. Jassim Daood. According to the ABC she noted, “a number of disciplinary cases have already been completed about some of the clinic’s other staff”. The scale of potential problems becomes clear when one considers the implants have never been approved for use, eager staff have little or no training and post-implant support regimes are entirely absent. For over a decade these implants have been available via the TGA’s Special Access Scheme, which is designed to allow patients access to otherwise unavailable drugs to treat conditions deemed potentially fatal in the absence of that drug.

In this case the Scheme is being exploited as a loophole whilst the implant option itself has left in it’s wake a litany of failure and fatalities. Colquhoun is unlicenced to perform ROD but ignored requests from the NSW Health Department in mid 2010. SMH wrote on October 20:

Despite this direction, Colquhoun resumed the treatments while still unlicensed between July and September of that year, only desisting when Grace Yates, a 23-year-old with a five-month-old baby, was given ROD and naltrexone at the clinic on September 29, 2010. She suffered a heart attack and died two months later, having never regained consciousness.

It’s worth considering this failed treatment option is likely to be expanded under a coalition government. As health minister in the Howard Government, Tony Abbott provided the funding for the launch of the evangelical Drug Free Australia from the Tough on Drugs/Assets of Crime kitty. Describing themselves as “Australia’s Peak Drugs Body” they failed to meet the conditions of the funding, choosing instead to sabotage related health policy basics. Without doubt they have proven to be to addiction treatment what the Australian (anti) Vaccination Network is to the management of vaccine preventable disease.

Abbott also sent $50,000 they way of Psych ‘n’ Soul in the same year, showing exceptionally poor judgement. There is little doubt with enemies of Harm Minimisation such as Bronwyn Bishop, Sophie Mirabella and Christopher Pyne on his proposed front bench, Australia’s strong evidence based approach to addiction management would suffer. As the coroner noted:

It appears that a patient only had to present at the clinic to be enthusiastically recommended for rapid opioid detoxification, no matter what their history or situation, without alternatives being discussed or considered or any information given out of the risks involved.

Another death related to the attempts at ROD Psych ‘n’ Soul is now infamous for, involved Michael Poole, 48. He was described as “delirious and delusional” after ROD and died at the Prince of Wales Hospital in Sydney two days later. The third death involved James Unicomb, 23 who died from drug toxicity following a poly-drug overdose, which followed the ROD and occurred whilst an implant remained active. This lack of appropriate follow up of patients is perhaps the most appalling failure related to the practice of ROD and implants.

Rapid detox’ doesn’t treat addiction. It removes cravings and leaves patients open to the possibility of overdose. Often they are dependent upon high doses of benzodiazapines which raises the risk of opioid induced respiratory depression. As addiction is not treated, behaviour cannot be expected to change. It is for this reason follow up should form the most important aspect of rapid detoxification. It is for the same reason that implants have such a high failure rate in “curing” addiction.

One can only imagine the profit made and moral crusading accomplished from treating now dead addicts who were essentially exploited, not treated. Of course, testimonials abound. Whether it’s those who adore Reece for showing them the way to Jesus or Colquhoun’s (third time lucky) performer in the below video, let’s not kid ourselves. The dead cannot speak.

Alex Wodak, director of Sydney’s St. Vincents Hospital Alcohol and Drug Service observed:

How they are allowed to be used for routine purposes in several states in this country beats me. It goes against all the normal regulations and I think the only explanation I can understand is that this is allowed in this case because they’re only drug addicts. […] We really need a national independent inquiry into the regulatory failure, the serious regulatory failure that’s gone on with Naltrexone implants for over a decade.

Indeed we do.

Naltrexone implants backed by zealotry but not evidence

Psych ‘n’ Soul Naltrexone Deaths Inquest Findings