Coronavirus pandemic prompts increased transparency of drug companies

The unprecedented nature of the SARS-CoV-2 coronavirus pandemic has begun to influence the transparency of drug company trials of potential COVID-19 vaccines.

On September 17th The New York Times reported that Moderna and Pfizer were releasing the protocols that describe the trial process to test a potential COVID-19 vaccine. On September 19th they reported that AstraZeneca had done the same. This heralds a significant change on the part of drug companies. Although in practice complex vaccine trial protocols would need to be interpreted by say, science journalists, in order to be understood by the wider public particularly given the multicultural nature of today’s communities in developed nations.  [See references below for protocols]

As trials have progressed to Phase III in which data on the safety and efficacy of vaccines are collated, the interest of the public has grown significantly. Intense media attention surrounded the recent pause of the Phase III trial of the vaccine being developed by AstraZeneca in partnership with scientists from Oxford University. Not surprisingly public interest has turned to pressure for more transparency as to how trials are conducted.

From July 24th to August 7th Ipsos surveyed respondents from 27 countries [PDF] on attitudes toward a COVID-19 vaccine. 74% of respondents said they would have a vaccine if it was available. The most common reason for rejecting the vaccine was concern over side effects (56%). This was followed by doubt of its effectiveness (29%). The importance of transparency surrounding Phase III trials is confirmed by the weight of these two reasons for rejecting the vaccine.

These vaccines are being developed rapidly under the gaze of a public that expects at some time to be given such a vaccine. It’s understandable that anxiety surrounding both efficacy and safety of COVID-19 vaccines existed long before the specifics of Phase III trials became public. That those specifics have become better understood due to an issue with safety does raise matters of trust within the public.

Of course the increased attention over safety and efficacy would never have arisen during development of the many so-called “alternatives” to regulated vaccines. Alternative products are not subject to reliable scrutiny and as such the acute and chronic effects are in fact undocumented or unknown. The safety and efficacy of such listed (as opposed to regulated) therapeutic products is almost always merely assumed.

Establishing trust between the public and the government and health authorities is important. Increased transparency of vaccine trials will help promote trust. Sustaining trust is significantly reliant on clear information and explanation of complicated issues that raise public concern. This is particularly true in the present environment where changing evidence may come across as inconsistency and if left unacknowledged may lead to suspicion. The proper interpretation and presentation of available information is essential.

Normally data gathered during a trial are published after the trial. However the dynamic nature of COVID-19 vaccine development and the global impact of this pandemic have already changed what may be considered normal. Added to this is information that is leaking out. The Oxford trial has recommenced on the advice of an independent safety committee. AstraZeneca announced that they “had not confirmed a diagnosis” of transverse myelitis in the study volunteer.

What has also recently become apparent is that the study was paused in July after a male volunteer who had received one dose of the vaccine developed transverse myelitis. See page 10 of this participant information sheet. There was a review by independent experts. The trial resumed after it was determined that the individual had a previously undiagnosed case of multiple sclerosis unrelated to the vaccine. Still, there was a persistent concern that AstraZeneca had not revealed in detail what had happened to the woman whose significant neurological symptoms led to the most recent trial pause.

On the September 14th edition of The Health Report Dr. Norman Swan interviewed Professor Bruce Neal, Executive Director of the George Institute Australia. The occasion was to discuss the launch of a project called Join Us. A challenging issue about Phase III trials is that drug or vaccine development may stall or fail due to lack of suitable participants. This isn’t due to drop out or resistance. Rather the cost and administrative difficulty of finding suitable participants is significant. Join Us aims to secure pre-consent to trials of a certain nature.

Whilst that’s interesting information about trials, Swan also asked Professor Neal about his thoughts on the reluctance of AstraZeneca to reveal details about the woman responsible for the second pause of the Phase III trial. Neal considered reasons to release more information. It would give a heads up to other researchers around the globe allowing them to “provide input and information into it”. However he also noted that releasing such information midway through a trial may have negative consequences.

There may be confidentiality issues as such a “severe unusual event” might lead to patient identity being leaked. Perhaps most interestingly was the observation that the trial may well end with a conclusion that the event was not an issue related to the vaccine. By then the damage is done. The public have already internalised the notion of a negative side effect. The media effort to reverse that belief is not likely to be successful.

Professor Neal stated;

And so the media surrounding the announcement of something like that is going to retain much more prominence probably than the media that tries to reel that back in and say, look, actually it wasn’t an issue. And that could have ramifications down the track when you try to get people to take the vaccine.

It’s important to note that the FDA has not allowed the AstraZeneca trial to resume in the US. The National Institutes of Health stated that it remains to be seen if the illnesses are coincidental and that, “pausing to allow for further evaluation is consistent with standard practice”.

Understandably some health professionals in the US remain concerned. Whilst investors were told of the second problem it has become clear that the company did not immediately alert the F.D.A. and advise them of the independent safety board’s recommendation to pause the trial. Virologist Dr. Peter Jay Hotez based at Houston’s Baylor college of Medicine has not been impressed. He claimed communication has been “horrible and unacceptable” citing the failure of UK regulators to provide rationale for resumption of the trial.

The New York Times also reported;

Dr. Paul Offit, a professor at the University of Pennsylvania and a member of the F.D.A.’s advisory committee on vaccines, said that it’s unclear how the company — or the U.K. government — determined that the second case was not related to the vaccine.

Offit has also noted that the rarity of transverse myelitis in the general public has not been reflected in the UK trial population. The extra caution we are seeing in the US is reason for the public to have increased confidence in the influence regulators have over the safety of vaccine trials. Consequently there is reason for the public to be less anxious about the safety of COVID-19 vaccines that are eventually marketed. Given that independent safety experts in the UK have advised it is safe for the Oxford trial to resume it will be very interesting to see what further evaluation by US authorities concludes.

There has been research into immunisation and the likelihood of subsequent development of transverse myelitis (TM) and acute disseminated encephalomyelitis (ADEM). Key points from the 2016 paper Acute Demyelinating Events Following Vaccines: A Case-Centered Analysis are as follows;

Results: Following nearly 64 million vaccine doses, only 7 cases of TM and 8 cases of ADEM were vaccinated during the primary exposure window 5-28 days prior to onset. For TM, there was no statistically significant increased risk of immunization. For ADEM, there was no statistically significant increased risk following any vaccine except for Tdap (adolescent and adult tetanus, reduced diphtheria, acellular pertussis) vaccine. […]

Conclusions: We found no association between TM and prior immunization. There was a possible association of ADEM with Tdap vaccine, but the excess risk is not likely to be more than 1.16 cases of ADEM per million vaccines administered.

Acknowledging vaccine safety concerns as a cause of vaccine hesitancy, in July this year Nicola Principi and Susanna Esposito published a narrative review, Do Vaccines Have a Role as a Cause Of Autoimmune Neurological Syndromes?

The authors wrote in part in their abstract;

Only well-conducted epidemiological studies with adequate evaluation of results can clarify whether a true association between vaccines and adverse event development truly exists. Autoimmune neurological syndromes that follow vaccine use are among these. […]

Literature analysis showed that most of the associations between vaccines and nervous system autoimmune syndromes that have been reported as severe adverse events following immunization are no longer evidenced when well-conducted epidemiological studies are carried out. Although the rarity of autoimmune diseases makes it difficult to strictly exclude that, albeit exceptionally, some vaccines may induce an autoimmune neurological disease, no definitive demonstration of a potential role of vaccines in causing autoimmune neurological syndromes is presently available. Consequently, the fear of neurological autoimmune disease cannot limit the use of the most important preventive measure presently available against infectious diseases.

The Institute for Vaccine Safety at Johns Hopkins University logically argues that a number of vaccines “may prevent transverse myelitis”. The institute published Do Vaccines Cause Transverse Myelitis? Last updated September 18th 2020 the article opens with the conclusion;

Natural viral infections with influenza, hepatitis A, measles, mumps and rubella and varicella have all been associated with myelitis, albeit rarely. Thus, these viral vaccines may prevent transverse myelitis by protecting against natural infection. Vaccines currently routinely recommended to the general population in the U.S. have not been shown to cause transverse myelitis.

Ultimately this research in conjunction with the cautious US approach at present does not support a contention of general recklessness in the production of this vaccine or of other potential COVID-19 vaccines.

This dynamic provides yet another blow to anti-vaccination conspiracies. Namely the contention that there is collusion between drug companies and health regulators to suppress the supposedly inherent dangers of vaccines that anti-vaxxers wrongly insist lead to an abundance of vaccine injuries. More so Dr. Paul Offit has been derided, verbally attacked and threatened by the global anti-vaccine lobby for many years as a callous profiteer of vaccines. Yet he has constantly raised a voice of caution to ensure safe COVID-19 vaccine development.

It is certain that placing the AstraZeneca trial on hold following advice from the F.D.A. is not a unique event. Rather the fact that measures employed to control the current pandemic are being played out before the public in real time has provided insight into events that are usually ignored. In the previous post I listed some other aspects of anti-vaccine conspiracy that simply cannot be sustained following media reports of the AstraZeneca/Oxford Phase III trial pause. Even cursory attention to the details of this trial has exposed the dishonesty of anti-vaxxer claims.

Well before the trial pause led to media attention, public anxiety and now transparency of drug companies, the importance of trust in accepting a COVID-19 vaccine had been raised in Australia. Prime Minister Scott Morrison made a significant mistake with respect to public confidence in vaccine development and uptake. In August he announced that Australia had signed a deal to produce the vaccine being developed at Oxford University if Phase III trials were successful.

His mistake was to add that it would be “as mandatory as you can possibly make it”. Morrison realised the mistake and in under a day had produced the anticipated walk back. Nonetheless the many anti-science and anti-reason groups that are feverishly misrepresenting the motives of governments and health authorities during this pandemic were delighted. Within hours of Morrison’s announcement the AVN published a video mocking the notion of “safe and effective” vaccines whilst contending they “had always known this was coming”.

There were of course no “walk backs” from the AVN when Morrison corrected his position. Pushing fear of mandatory vaccination has always translated to profit for this group and Scott Morrison had done them a favour. Say no to mandatory vaccination read the back of a T-Shirt weeks later in Perth during Australia-wide “solidarity” rallies. Messages on social media continue in the same vein. Still, the reality is that messages and memes on mandatory vaccination would be common had Scott Morrison made no such statement.

Any harm done to the uptake of a COVID-19 vaccine in Australia is likely negligible. A survey conducted in April found that just under 86% of Australians aged over 18 would get a COVID-19 vaccine. 4.9% would not whilst 9.4% were indifferent. These figures are promising but were collated before the widely publicised pause in the AstraZeneca trial and increased public reflection on the safety of a COVID-19 vaccine. Survey responses were to the statement, If a COVID-19 vaccine becomes available, I will get it.

Ipsos published their global attitudes results on September 1st, indicating an 88% uptake of a COVID-19 vaccine in Australia. 59% strongly agree and 28% somewhat agree with the statement, If a vaccine for COVID-19 were available, I would get it. Only China and Brazil were more likely to accept a vaccine. These figures were also collated before the pause in the AstraZeneca trial. Follow this link to read Key Findings for Australia.

Another area that’s causing anxiety is the posturing of Donald Trump toward authorising a COVID-19 vaccine before the upcoming election. Consider the measure of Trump for a moment. He will tempt the voters with the promise of a vaccine in weeks. However it is more realistic to expect a safe and effective COVID-19 vaccine in months. These promises demand a disregard for vaccine safety. Yet in March 2014 Trump was tweeting in support of the mythical vaccine/autism link, a bogus view that bemoans a lack of vaccine safety. After the last election, research fraud and vaccine/autism profiteer Andrew Wakefield attended an inaugural ball from which he posted a social media video calling for an overhaul of the CDC.

Others have long ago considered the measure of Trump in regard to the election and a COVID-19 vaccine promise. In early June University of Pennsylvania professors Dr. Paul Offit and Dr. Ezekiel Emanuel wrote an opinion piece in The New York Times entitled Could Trump turn a vaccine into a campaign stunt?

It included;

In a desperate search for a boost, he could release a coronavirus vaccine that has not been shown to be safe and effective as an October surprise. […]

Given how this president has behaved, this incredibly dangerous scenario is not far-fetched. In a desperate search for a political boost, he could release a coronavirus vaccine before it had been thoroughly tested and shown to be safe and effective. […]

Thousands of Americans have already died as Donald Trump has perpetually postponed effective public health interventions and made poor therapeutic recommendations. We must be on alert to prevent him from corrupting the rigorous assessment of safety and effectiveness of Covid-19 vaccines in order to pull an October vaccine surprise to try to win re-election.

At the beginning of the second week of September the CEOs of nine drug companies, arguably competing in the development of a COVID-19 vaccine, signed a pledge to stand with science and not launch such a vaccine until it met “high ethical standards and sound scientific principles”. The pledge statement as it appears on Pfizers website is in references below. It came at a time when public health specialists and scientists expressed concern that the Trump administration was pressuring regulators to authorise a vaccine before the November 3rd election.

The New York Times reported;

The joint statement by competitors was seen as an effort to restore public trust as President Trump has pushed for a vaccine before the presidential election.

An out-take from the pledge from Pfizer’s website is as follows;

Following guidance from expert regulatory authorities such as FDA regarding the development of COVID-19 vaccines, consistent with existing standards and practices, and in the interest of public health, we pledge to:

  • Always make the safety and well-being of vaccinated individuals our top priority.
  • Continue to adhere to high scientific and ethical standards regarding the conduct of clinical trials and the rigor of manufacturing processes.
  • Only submit for approval or emergency use authorization after demonstrating safety and efficacy through a Phase 3 clinical study that is designed and conducted to meet requirements of expert regulatory authorities such as FDA.
  • Work to ensure a sufficient supply and range of vaccine options, including those suitable for global access.

We believe this pledge will help ensure public confidence in the rigorous scientific and regulatory process by which COVID-19 vaccines are evaluated and may ultimately be approved.

Yes to the cynical eye this may seem to present the pharmaceutical CEOs as really great guys. However I recommend reading the entire Biopharma Leaders Unite pledge. More to the point with increased transparency the public and the media have an invested interest to see a suitable outcome here. This pledge is certainly a step up from Fauci saying he has “confidence and some faith” that the COVID-19 vaccine approval won’t be political.

Earlier in the year it was reported that a significant number of Americans are likely to refuse a COVID-19 vaccine. A robust anti-vaccination lobby and rising numbers of the vaccine hesitant mean that the number of Americans who accept the vaccine may be insufficient to sustain herd immunity, which may require between 50 – 70% of the population to be immune. The more recent Ipsos survey found 67% of US citizens would have the vaccine.

Exactly how many must be vaccinated to achieve herd immunity is still uncertain. The WHO suggest 95%. Mathematical modelling reflecting age and social activity level produces a herd immunity “illustration” as low as 43%. Other reports suggest a vaccine uptake of over 70% is needed. The Mayo clinic point out that reaching this level of immunity through infection and not vaccination would overwhelm the health system and cause millions of deaths.

Thus there is ample reason to hope greater transparency of vaccine trials leads to justified improved confidence in the safety and efficacy of COVID-19 vaccines and increased uptake. Of course given the speed of current COVID-19 vaccine trials let us also hope that the vaccines that make it to market are extremely safe and splendidly effective. The fewer challenges that accompany immunisation on a global scale the better.

Another area that is getting more scrutiny if not exactly transparency is that of vaccine nationalism. This term refers to agreements between governments and vaccine manufacturers that ensure developed nations have secure access to vaccines for their entire population before they are available for other nations. With COVID-19 this may result in a delay in vaccinating health workers in developing nations, individuals at high risk of severe disease or death and those living in a region of a sudden dangerous cluster.

COVID-19 is a global pandemic. Yet we are faced with a situation where wealthy nations will be able to vaccinate their populations whilst countries that rely on aid organisations will be unable to vaccinate health workers and at-risk populations without organised help. A recent Science Friction podcast looks at the ways in which this problem can be combated. Australia’s Friends of Science in Medicine actively support equitable access to “COVID-19 vaccines and related health technologies”.

No doubt the anti-vaccine lobby will use information in the trial protocols in the same way they use vaccine package inserts. Thanks to exceptional cognitive dissonance they will list reasons as to why information from vaccine manufacturers can’t be trusted whilst using that same information to defend these reasons. The good news is that as we’ve seen, increased transparency and media attention has exposed tenets of anti-vaccine conspiracy and beliefs as vacuous and fallacious. On these points it’s a case of watch this space.

In conclusion it can be seen that the increase in transparency of COVID-19 vaccine development should indeed serve to increase public trust and confidence in the quality of eligible vaccines. I cannot finish without stressing again that the safety and efficacy elements of Phase III trials do not apply to the raft of concoctions marketed as alternatives to medicine. All consumers should seek reputable sources of information and beware of the many hoax “cures” of COVID-19. Discuss any novel plans to manage or prevent COVID-19 with a registered medical practitioner.

Finally whilst the importance of transparency with respect to vaccine trials has become clear, it was also confirmed by the Ipsos global survey on attitudes to a COVID-19 vaccine. The most common reasons for intending to refuse a vaccine are safety followed by efficacy. The establishment of which is the very aim of Phase III trials.


REFERENCES

Phase 3 clinical trial of investigational vaccine for COVID-19 begins

Moderna Clinical Trial Protocol – SARS-CoV-2 vaccine

Pfizer Clinical Trial Protocol – SARS-CoV-2 RNA vaccine

AstraZeneca Clinical Trial Protocol – COVID-19 vaccine

Oxford Vaccine Trials – Participant Information Sheet: COV002 (July 2020)

Oxford Vaccine Trials – Participant Information Sheet: COV002 (Sept. 2020)

Willingness to vaccinate against COVID-19 in Australia

9 in 10 Australians say they would get vaccinated for COVID-19 – Ipsos

Global attitudes on a COVID-19 vaccine – Ipsos [PDF]

A future vaccination campaign against COVID-19 at risk of vaccine hesitancy and politicisation

Biopharma Leaders Unite To Stand With Science – Pfizer

Moderna and Pfizer reveal secret blueprints for coronavirus vaccine trials – NYT

AstraZeneca under fire for vaccine safety releases trial blueprints – NYT

Do Vaccines Cause Transverse Myelitis? – Institute for Vaccine Safety, John Hopkins University Dept. of International Health

Acute demyelinating events following vaccines: a case-centered analysis
– DOI: 10.1093/cid/ciw607

Do vaccines have a role as a cause of autoimmune neurological syndromes?
– DOI: 10.3389/fpubh.2020.00361

FSM supports equitable access to COVID-19 vaccines

Vaccine nationalism threatens global plan to distribute COVID-19 shots fairly

The rise of vaccine nationalism – should we be worried? – ABC Podcast

Herd Immunity: Understanding COVID-19 – DOI: 10.1016/j.immuni.2020.04.012

How the Oxford trial pause challenges anti-vaccine conspiracies

Recently the Oxford COVID-19 vaccine trial was paused due to a possible case of transverse myelitis in one of the subjects. Today (Saturday UK time) it was announced that the trial would resume following advice from from safety experts.

Confirmation Update: Transverse myelitis has not been diagnosed in the subject [1], [2], [3], [4].

The news of the pause had the anti-vaccine lobby reacting with as much composure as dozing picnickers who have awoken to find they are laying atop a large nest of very active fire ants.

There is the urge to proclaim we told you so. Yet this includes the realisation that forfeiture of key pegs in anti-vaccine conspiracy is required. What has followed as we see below appears to be confusion, the inability to comprehend events, fabrication of fallacy and bogus reinforcement of elements of the Big Pharma conspiracy.

It’s important not to underestimate how disturbing genuine challenges to an individuals world view can be. In the case of the Oxford trial announcement, the anti-vaccine conspiratorial view of the world is threatened by a distressing reality. For the dedicated anti-vaxxer this leads to uncomfortable cognitive dissonance. In fact anti-vaccine conspiracies must exist in the first place to resolve the cognitive dissonance that arises when scientific evidence and epidemiology overwhelmingly refute the myth of dangerous vaccines and manufactured claims of vaccine injury and death.

In this case there are three main challenges to current anti-vaccine beliefs.

  1. The MSM (mainstream media) presented a transparent account of the Oxford trial pause.
  2. The pause in the trial itself shows that the safety aspect of Phase III clinical trials is working well.
  3. Cursory reading of the situation confirms the efficacy component of Phase III clinical trials and the use of a placebo.

The anti-vaccine lobby contend that mainstream media are biased against the “truth” of vaccine horror because what is reported is not anti-vaccine. If the mistake of giving anti-vaccine identities air-time to push unsubstantiated disinformation is made, criticism swiftly follows. Yet primarily it is the industry requirement to fact check that keeps anti-vaccination views from being presented unchallenged.

It’s more likely that their antics make tabloid or news segments because they are dishonest and at times vindictive. This attracts regular criticism of the Australian Vaccination-risks Network. A scheme by anti-vaxxer Kyia Clayton to interview AVN president Aneeta Hafemeister on ABC Hobart was met with outrage. It was justly criticised on Media Watch which yet again led to Meryl Dorey urging members to bombard the ABC and ACMA with complaints.

Rather than rise to the occasion and present evidence that meets the standard of scientific consensus the AVN has instead accused the media of being part of the larger conspiracy. Attacking mainstream media and articles that are based on vaccine fact is a substantial activity for Australian anti-vaxxers.

A constant claim of anti-vaxxers is that vaccines are never tested adequately for safety. This is partly due to the erroneous belief that vaccines are so full of dangerous chemicals and biological matter that they cannot possibly be safe. Ergo, any genuine monitoring for adverse reactions in large samples would reveal that a high percentage present with such reactions. As this is not the case their only conclusion is the biased testing conspiracy.

Another claim is that vaccines are never tested for efficacy. They don’t work and we have all been deceived. Herd immunity is a fake concept. Vaccines were introduced after improved sanitation and hygiene eliminated most disease and thus deserve no credit. This claim is made with the help of deceitfully crafted graphs plotting mortality, not morbidity, in such small numbers it appears that vaccines had no impact. The two claims specific to Phase III clinical trials are often made together.

This was clear when the AVN responded to an August 2019 SMH article by Liam Mannix, Anti-vaxxers live in an online bubble this scientist wants to burst. Their response is a strange collection of “propositions” the author angrily contends must exist, whilst citing pseudoscience and articles relating to medication, not vaccines.

The AVN piece included this under “Proposition 4”;

…there have never been double-blind, placebo-controlled prospective studies done on either the safety or efficacy of vaccines, not even when a new vaccine is introduced.

Oh my. This persists despite accessible evidence to the contrary and available WHO recommendations. More so, in line with all anti-vaxxers the AVN argue their definition of a placebo (such as saline) is what should be used in vaccine trials. In fact it is used in many trials but the AVN choose to ignore this. This may include shifting the goal posts. Virology Down Under discuss this no true Scotsman anti-vax fallacy related to placebos.

In some vaccine trials a saline placebo is not ethically suitable and the placebo used is not inert. With respect to the urgency COVID-19 presents this article argues that placebos aren’t needed for vaccine challenge trials. In the Oxford trial a non-saline placebo functions as a more effective control as Dr. Norman Swan explains below. The AVN have always objected to Gardasil studies which used AAHS (the amorphous aluminium hydroxyphosphate sulphate adjuvant) as a placebo.

Without citing any reference the AVN offer their definition of a vaccine trial placebo;

By definition, a placebo must be a totally inert substance which will never provoke a response.

In a recent Coronacast episodeThe Oxford vaccine’s troubles. Why it’s not doomed (yet) Norman Swan talked about efficacy and safety in this vaccine trial. Whilst the USA are using a saline placebo, the other participant countries are not. Swan explains;

A few weeks ago, phase 2, phase 3 studies, that’s dose finding and whether or not the vaccine works in large numbers of people and whether it safe, started in Brazil, South Africa and the UK, and they were aiming to recruit 17,000 people. There was also a phase 3 study just beginning in the United States in about 80 sites, trying to recruit about 30,000-odd people. The aim is to have a trial of about 50,000 people.

And interestingly it’s a placebo-controlled trial but the placebo is not saline. It is in the United States, but in Brazil, South Africa and the UK it’s actually not a dummy drug, it’s not saline, it’s a meningococcal vaccine, and they are doing that so that people don’t recognise whether or not they’ve had a placebo. It’s very important in a placebo-controlled trial that you don’t know that you are in the placebo arm. And if you get a shot in your arm and nothing happens and it’s pretty mild you think, well, maybe I’m in the placebo group.

The presenters talk about the seriousness of transverse myelitis and Norman Swan offers this context;

However, there was a study not so long ago which looked at 64 million vaccine doses and really found very little evidence, if any, that transverse myelitis is caused by immunisation. Out of 64 million doses they found seven cases or eight cases that may be associated with it. And they look really widely. They didn’t just look at the week after you’ve had the immunisation or the month after, they looked at almost any time after you’ve had the immunisation, and they conclude that transverse myelitis, unless in very rare circumstances, is not caused by a vaccine. […]

So what they’ve got to find out with this person is are they in the placebo arm, are they in the active arm, is it really transverse myelitis, what are the antibodies that have actually been shown? Are there any other symptoms? And did the person actually get infected with real COVID-19 after the trial had started…

I recommend reading the transcript or listening to this episode of Coronacast. Tegan Taylor and Swan talk more on Phase III trials and discuss the specifics of the Oxford vaccine. It’s an adenovirus carrying genetic material into cells to instruct the cells to produce fragments of COVID-19 virus. It is these fragments that induce an immune response. With respect to the use of placebos in vaccine trials a July 27th episode examines the ethics associated with the fact that subjects in the placebo arm of Phase III trials are not receiving a vaccine.

By the time the Oxford podcast was published on Thursday the AVN was already suggesting on Facebook that there may be more adverse reactions hidden from the public.

AVN Facebook post

Dubious message on AVN Facebook

“It does raise questions”? The problem with the above post is the apparent interpretation by an AVN Facebook administrator that one of the “close friend daughters” who took part in the Oxford trial “is in the Royal” [London Hospital], “diagnosed with Transverse Mylytis” (sic). There is an unverified claim that, “they have asked to keep this quite (sic) as they don’t want the public to know”. The AVN admit the information may not be true.

Yet is this really evidence of a covert case of transverse myelitis? Perhaps Karen McNab is referring to a) her friend’s daughter and also b) the “volunteer” mentioned in the WhatsApp message. The trial subject who had the presumed adverse reaction is a woman who is in hospital.

Of course my interpretation could be wrong. There is however no clear statement that one of the friend’s daughters has transverse myelitis.

Some AVN members were justifiably suspicious.

AVN FB members question source

Rixta Francis, a long term AVN member prone to simply inventing disinformation published her predictably outrageous fallacy of the Oxford trial. This is an excellent example of an immediate, and  feverish attempt to slap at the fire ants of cognitive dissonance. Fellow members are supportive.

Facebook: Rixta Francis misleads over Oxford COVID vaccine trial
Self published author of The Fiction of Science Rixta is prone to reinterpret reality in the manner above. To appreciate this we need to explore her approach more fully. In an interesting example of how things come round in circles Francis is infamous for her abuse of the memory and parents of baby Riley Hughes, who featured in the SMH article I mentioned above.

Riley died from pertussis in March 2015 before he was old enough to be vaccinated. Feeling a need to educate parents about immunisation Catherine Hughes began the Light For Riley campaign. She now runs the Immunisation Foundation of Australia. Ten months after the death of Riley, Francis falsely claimed Catherine was a member of Stop the AVN, suggested Riley and his pertussis had never existed or that the parents killed infant Riley themselves.

The post below suggests the Oxford adverse reaction has been staged. It includes dismissal of genuine media intention, dismissal of safety and dismissal of efficacy helped by quoting Australia’s CSIRO. Again this is textbook management and minimisation of cognitive dissonance.

AVN Facebook post

Other comments in the thread follow a similar theme and manage to reveal quite ridiculous thought processes. The reason people placed themselves at such risk is because they were offered “a small fortune… it all comes down to money”. Vaccines always cause “horrific injuries”. We “can’t cure cancer but we can make a vaccine in six months for a disease we don’t understand?”.

It will be interesting, but not surprising, to see how this group reacts to the news that the trial has resumed.


Further reading:

Oxford Vaccine Group

Oxford vaccine trial – University of Oxford

How Vaccine hesitancy could undermine Australia’s COVID response – The Guardian, September 12th 2020

Fact Check: Mastercard partnership on vaccination records is unrelated to finances – USA Today, September 9th 2020

Halting the Oxford vaccine trial doesn’t mean it’s not safe – The Conversation, September 9th 2020

Vaccine testing and approval process – CDC

 

 

Meryl Dorey suddenly believes viruses can only be transmitted by injection

The driving force behind the Australian Vaccination-risks Network is Meryl Dorey who is tagged on this blog, and was highly active at the time of the HCCC Public Health Warning about this group.

Thanks to a tweet by a highly effective critic of the AVN my attention was drawn to a post Meryl made on her Facebook page during a live video broadcast on April 11th this year. What I found compelling was that suddenly – and I do mean suddenly as Dorey had never made this claim before – she announced that her “personal opinion is that viruses can only be transmitted by injection”. As we’ll see this causes problems for one particular anti-vaccine position Meryl has promoted.

The comment below was posted in the context of discussing viral testing and the strange notion of buying “a private test”, presumably to avoid the COVID conspiracy pitfalls. The last sentence contains Meryl’s view about viral transmission by injection. This pattern of adopting stand out themes of conspiracy theories is one Meryl Dorey has followed for years.

Meryl Dorey: viruses only transmitted by injection

Source: Comment 32

The compelling aspect to Dorey’s sudden revelation is that this claim had already been made 12 days earlier by anti-vaxxer and erstwhile Involuntary Medication Objectors Party candidate, Tom Barnett. The video in which he made his claims was removed from Facebook and YouTube.

Barnett claimed in the video;

You can’t catch a virus; it’s impossible. The only way you can catch a virus is by having it injected into your bloodstream.

I say. Meryl apparently decided this sounded pretty good to however she is planning to profit from the COVID-19 crisis. Feel free to search her online material prior to Tom Barnett’s comments for a statement suggesting Meryl Dorey believes viruses can only be transmitted by injection. I for one am having trouble finding such a reference.

Claiming to hold such a position enables one to reject the need for immunisation and to argue that vaccination against viral disease may in fact be the cause of the disease.

Meryl is clearly spinning more plates than is wise with this latest addition of evidence denial. To be specific, her claim that viruses can only be transmitted by injection is a form of germ theory denial |Wikipedia|. Denial of germ theory |Wikipedia| is as old as germ theory itself. Thanks to germ theory significant advances in personal hygiene and public sanitation have brought about improvements in health and reduction in the spread of disease.

Which brings us to a real problem for Meryl Dorey. She claims that vaccinations have done almost nothing, if not absolutely nothing, to prevent disease. She has fallaciously argued before that the documented fall in vaccine-preventable disease is in fact due to better hygiene, diet and sanitation and occurred before the introduction of vaccines. This is very common misinformation pushed by anti-vaxxers usually with heavily doctored graphs that chart disease mortality as opposed to morbidity and are falsely attributed to official sources.

It fails utterly to explain the success of vaccines introduced in the later half of the 20th century such as measles (1963) and haemophilus influenzae type b (1993). The WHO do a good job of dispelling this misinformation here. At the beginning of 2012 I looked at the AVN’s use of this myth and included an explanatory video with audio from both Meryl Dorey and Judy Wilyman.

In it we hear Dorey during a radio interview with Helen Lobato on Melbourne’s 3CR in December 2011 make the familiar claim;

Meryl Dorey: A lot of the credit that’s been given to vaccines for the decline in deaths and infectious diseases has nothing to do with vaccines. Because it all happened before the shots were even introduced.

Helen Lobato: Mmmm… and it was more the diet and the sanitation?

Meryl Dorey: That’s right. Engineers did more to improve the health of Australians than doctors ever have.

You might like to listen to Meryl on the audio player below;

 

Looking back at Dorey’s frequent promotion of this misinformation on the AVN website, social media and other media it is impossible to find any clarification specific to viral infection being only possible by injection. Nor is there any delineation between bacterial infection and viral infection being controlled by sanitation.

Thus in one foul swoop Dorey has removed the logic behind her claim that sanitation, not vaccination, brought about the control of specific viral infections. If viruses can only be transmitted by injection then improved sanitation must only be responsible for reducing infectious diseases caused by bacteria.

This also removes her concerns over “vaccine shedding” [1], [2] with respect to vaccines designed to prevent viral infection. This is highly significant concerning Dorey’s new claim as material presented to defend the notion of unbridled “vaccine shedding” refers exclusively to viral shedding in stools or in the case of LAIV nasal spray, in nostrils.

As Meryl Dorey and the AVN have challenged health ministers and authorities to accept being injected with a body weight adjusted equivalent of the entire childhood vaccine schedule, I do hope there is no intent to demonstrate strength of conviction by ingesting or inhaling any viral material associated with disease.

Therefore as it now stands I would be fascinated to know how Meryl Dorey intends to justify believing that sanitation, not vaccination, reduced the spread of viral disease given her claim that viruses can only be transmitted by injection.

 

Call to action on anti-vaccination bus tour

© Australian Skeptics Inc.

By Tim Mendham

July 19th 2020

Australian Skeptics has issued a warning and call to action to Australian media, medical professionals, and local councils regarding the current anti-vaccination ‘revival’ tour of rural and regional Australia:

VAXXED Bus
Delivers COVID-19 Conspiracies and Bad Advice

The so-called “VAXXED” bus is currently touring Australia, spreading misinformation about vaccination at local ‘revival-style’ meetings, often in regional venues owned or managed by local councils or schools. This big black bus carries the logo of the “Australian Vaccination-risks Network” (AVN), an organisation whose leaders have:
● Claimed COVID-19 is nothing more than a bad cold.(1)
● Encouraged people to take photos in hospitals to show COVID-19 is not serious.(2)
● Discouraged face masks for COVID-19 and stated temperature testing is crazy and stupid.(3)
● Likened vaccination to rape.(4)
● Claimed microchips could be injected into the population via vaccines.(5)
● Promoted the falsehood that contrails from aircraft – which they call “Chemtrails” – are used to poison the population.(6)
● Spread the discredited falsehood that vaccines lead to autism.(7)
● Propagated the myth that SIDS and the fatal injuries suffered by some babies who were shaken to death are really the results of vaccines.(8)

With the recent resurgence of COVID-19 in parts of the country, now is not the time to have anyone spread disinformation about the pandemic or vaccine preventable diseases. It is clear from their own statements that the organisers of this tour do not take the threat of COVID-19 seriously.

In 2014, the NSW Health Care Complaints Commission issued a public warning against this organisation, stating in part:

Warning – The Commission has established that AVN does not provide reliable information in relation to certain vaccines and vaccination more generally. The Commission considers that AVN’s dissemination of misleading, misrepresented and incorrect information about vaccination engenders fear and alarm and is likely to detrimentally affect the clinical management or care of its readers.(9)

MEDICAL PROFESSIONALS: Should be aware that the VAXXED Bus may be visiting their area. This will mean that current and potential patients may be exposed to dangerous misinformation that can have deleterious if not fatal consequences. Anti-vaccine messages should be actively resisted, and we encourage local medical professionals to take a stand on this issue, either via local media, social media or whatever public avenues exist in their area.

MEDIA: We advise the media to take great care when covering the VAXXED Bus and the Australian Vaccination-risks Network. They use the tactic of “tell both sides of the story”, also known as “False Balance”, a misrepresentation that the ABC’s Media Watch has covered with regard to this organisation in 2012(10). The media are advised to focus on the more bizarre conspiracy theories propagated, but are under no obligation to give this group the oxygen they seek.

LOCAL COUNCILS: Should consider very carefully the possible consequences of hiring out venues to this organisation. With parts of regional Australia recording a worrying low level of vaccination in a time of a global pandemic, encouraging parents not to vaccinate their children is irresponsible.

“We have one of the safest outcomes when it comes to preventable diseases in the world, because of our strong immunisation program, and anti-vaxxers should just butt out. Vaccination has saved lives, it’s safe, it’s effective and anyone that tried to create any other discussion against it is really trying to harm the Australian public”
– Australian Medical Association President Dr Tony Bartone (Radio 2GB 20/04/2020)

“…there has been somewhat of an upsurge in paranoid and sort of unhinged behaviours.”
– AMA state president (SA) Dr Chris Moy (ABC NEWS 21/05/2020)

“It is concerning that the reports that I have received are that some people believe that coronavirus is a conspiracy or that it won’t impact on them.”
– Victoria’s Health Minister Jenny Mikakos (7 News July 2020)

References

1. The Australian Vaccination-risks Network is one group which has moved to downplay the significance of coronavirus, with spokeswoman Meryl Dorey saying the virus “is just the common cold”. “The cold can kill anyone if they’re sick to begin with and coronavirus is no different,” she said on a Facebook video on Sunday. She said people have been “fooled” by a “fear campaign on the silly sheep media”.
https://7news.com.au/lifestyle/health-wellbeing/anti-vaxxers-downplay-common-cold-like-coronavirus-amid-fears-of-forced-vaccinations-c-725089

2. Dorey questioned the COVID-19 pandemic saying: “Are you being lied to?” Requesting that followers “take your phones and pop into the local hospital” and “Let us know how crowded it is — or is not. Is coronavirus really overwhelming our nation or is our nation overwhelming us with lies and killing our economy and us?”
Hansen, Jane (3 April 2020). “Anti-vaxxers deny COVID-19 pandemic, urge others to ignore isolation advice”. The Sunday Telegraph. Sydney NSW.

3. On Face Masks for COVID-19: “… a piece of cheese cloth… something with lots and lots of holes in it is the best to wear.”
On Temperature Testing for COVID-19: “…. temperature testing, that’s just crazy….” “It is so stupid. It just shows the extent of stupidity that our government, our medical community and our media are displaying.”
Meryl Dorey, Under the Wire – https://www.bitchute.com/video/K77QIp3HJQyP (49min 20sec mark)

4. A controversial anti-vaccination group has likened vaccines that prevent disease to rape, drawing condemnation even from some its own supporters.
https://www.smh.com.au/national/australian-vaccination-skeptics-network-compares-vaccines-to-rape-20150422-1mr0wk.html

5. “The next and most logical step is the use of microchips which will contain all of the same information contained on smart cards but which will be injected into us and read and updated from a distance.”
http://web.archive.org/web/20010406083421/avn.org.au/big.htm

6. “The number of chemtrails sprayed over the #CDCWhistleblower #VAXtruth rally was shocking! Many of the protesters were sickened. Stop it NOW!”
Twitter @nocompulsoryvac – 1:15am – 27 Oct 2016

7. Meryl Dorey: “All vaccinations in the medical literature have been linked with the possibility of causing autism, not just the measles/mumps/rubella vaccine.”
https://www.abc.net.au/mediawatch/episodes/false-balance-leads-to-confusion/9973912

8. Anti-vaxxers come up with their most abhorrent lie yet. – “So Shaken Baby Syndrome again, like SIDS, is a waste basket. It is a way of blaming the family for what may have been caused by the medical community.”
https://www.mamamia.com.au/avn

9. The NSW Health Care Complaints Commission – Public statement – warning about the Australian Vaccination-skeptics Network, Inc. (‘AVN’), formerly known as Australian Vaccination Network Inc.
https://tinyurl.com/p6o4yy8

10. False balance leads to confusion (Media Watch ABC October 2012) https://www.abc.net.au/mediawatch/episodes/false-balance-leads-to-confusion/9973912

For reliable information about COVID-19: https://www.health.gov.au
For reliable information about vaccination: https://www.health.gov.au/health-topics/immunisation


Once again please note this post is © Australian Skeptics and the original can be sourced here.

Chris Kenny attacks Paul Barry, Media Watch and the ABC

Last month Chris Kenny used his programme The Kenny Report on Sky News to launch a knee jerk attack against Media Watch and particularly its host Paul Barry.

It would seem that the facts about hydroxychloroquine not supporting the constant praise Donald Trump gave it as a treatment or preventative for COVID-19 did not sit well with Mr. Kenny. He was having none of the notion that these facts and the manner in which the media did or did not report them could be accurately presented on Media Watch.

His frequently personal, highly opinionated attack on Paul Barry fails to present necessary evidence whilst liberally applying the very deception he accuses Barry of. Kenny’s numerous contentions have become somewhat more relevant in light of the WHO suspending its trial of hydroxychloroquine as a treatment for COVID-19 due to safety concerns. [Update: The WHO has resumed the trial of hydroxychloroquine after the study leading to the suspension was retracted by the Lancet. Full update after post]. However first some background on Trump and a review of the Media Watch segment in question.

The COVID-19 pandemic has produced a veritable cornucopia of weird and wonderful personalities making a range of deceptive, dangerous, conspiratorial or just plain wrong claims.

With respect to hydroxychloroquine as a treatment or prophylactic for COVID-19 the evidence and advice has, from the beginning, been clear. Trials were needed to establish if and how the drug should be taken. Within weeks treatment trials revealed serious problems and fatalities whilst warnings about its use as a prophylactic were unambiguous.

In the latter case warnings were more widespread after Donald Trump began to promote it. On March 19th in a White House press briefing Trump demonstrated a grave error of comprehension. Hydroxychloroquine has been used in the treatment and prevention of malaria for decades. Where suitable it is also prescribed in the management of rheumatic diseases such as rheumatoid arthritis and lupus.

In a textbook example of why scientific advisors must be consulted by politicians who comment on health matters, Trump’s error of reasoning was to assume this prior, specific use of hydroxychloroquine meant it was apparently safe for other uses. In a March 19 press briefing he said in part;

Nothing will stand in our way as we pursue any avenue to find what best works against this horrible virus.

Now, a drug called chloroquine — and some people would add to it “hydroxy-.”  Hydroxychloroquine.  So chloroquine or hydroxychloroquine. Now, this is a common malaria drug. It is also a drug used for strong arthritis. If somebody has pretty serious arthritis, also uses this in a somewhat different form. But it is known as a malaria drug, and it’s been around for a long time and it’s very powerful.

But the nice part is, it’s been around for a long time, so we know that if it — if things don’t go as planned, it’s not going to kill anybody.

Five days later after taking a form of chloroquine an Arizona man died from cardiac arrest and his wife was hospitalised. They had ingested chloroquine phosphate which is not a medicinal form of chloroquine.

Despite Trump’s enthusiasm for hydroxychloroquine Dr. Anthony Fauci had urged caution. The day after Trump’s briefing, during his own COVID-19 briefing, Fauci answered reporters who were querying the use of the drug as a treatment. He stated;

The answer is no, and the evidence that you’re talking about … is anecdotal evidence.

Nonetheless, Trump followed by tweeting the drug was a “game changer” and almost a month later on April 14th Trump was still confusing its prior use with presumed general safety [Media Watch – 16 sec mark];

What do you have to lose? They’ve been taking it for forty years for malaria.

That was quite a statement. Particularly given what we know now. Trump announced on May 18th he’d been taking hydroxychloroquine as a prophylactic for a week and a half. On May 20th he announced he would stop his “regimen” in a day or two. However almost a month earlier on April 24th the FDA had warned of the serious side effects of hydroxychloroquine [2]. They cautioned it should not be used outside a hospital or clinical trial.

The need for more research into the potential of hydroxychloroquine was reinforced by authorities from the very early days of Trump’s glowing praise for the drug. On the same day as his “what do you have to lose?” comment, it was reported that a high dose trial in Brazil looking at treatment of COVID-19 was abandoned due to a trend toward lethality.

On April 14th Science Alert reported in part;

After 11 patients died across both dosage groups, the team halted the high-dose arm of the trial on day six, citing more heart rhythm problems in the high-dose group, and “a trend toward higher lethality”.

Which brings us to the Media Watch segment, Hydroxychloroquine disappoints, of Monday April 27th. You can watch the segment (6.42) and access the transcript here. Or you can listen to the audio below or grab the mp3 file here (© ABC).

——————————–

Paul Barry does exactly what one would expect from Media Watch. He reported on findings from VA hospitals in the USA of higher mortality in those given hydroxychloroquine and the drug’s lack of efficacy. He stressed that the study was not randomised and hadn’t been peer reviewed, but was being taken seriously. He also reported on the disappointing trial results from Brazil and presented the well known tweets from Trump and Giuliani. The latter claiming a 100% success rate of hydroxychloroquine against COVID-19 was taken down by Twitter. Viewers were also presented with the chorus of hydroxychloroquine support from Fox News and quotes from Trump.

Shining a light on Australian media Barry quite fairly reported on Sky News Australia. After Dr. Fauci and others had warned hydroxychloroquine hadn’t been adequately tested and may be dangerous Sky reporters cited “Trump Derangement Syndrome” as the cause for US media reporting on the problems with Trump’s claims and the facts about the drug.

Rather than present evidence to support Trump’s claims or efficacy of hydroxychloroquine, Sky News contended that it was hatred of Trump that led to reporting of its dangers. Chris Kenny argued that the “real world clinical assessment of this drug at the moment”, was that doctors and dentists were “putting it aside” for themselves or their family.

Kenny also demonstrated the same grave error of comprehension as did Trump. On April 2nd he was promoting the claims of Dr. Vladimir Zelenko who had published a YouTube video making unverified claims about the efficacy of hydroxychloroquine given with zinc and antibiotics to treat COVID-19. The same method is known to cause cardiac problems.

Chris Kenny informed his viewers;

Now we know this drug is safe. People have been taking it for these other conditions for decades. So this does hold out great hope.

Yet Zelenko’s claims had already been exposed as unproven. Paul Barry noted it was reported on Snopes;

Zelenko’s claims, however, rest solely on taking him at his word: He has published no data, described no study design, and reported no analysis.

Zelenko’s video was rightly removed from YouTube. Kenny “wondered” if this censorship was due to Zelenko signing off his video with over the top praise for Trump. He professed his love, blessings and hope that God protects [President Trump]. It is now known Zelenko falsely claimed the trial he was enthusiastically promoting as successful had FDA approval. This has brought him to the attention of a US Federal prosecutor.

Paul Barry went on to note Alan Jones thought hydroxychloroquine should be “rushed into the front-line”. Again, as with Trump and Kenny we see the same lack of basic critical thought. Yes, Jones argued;

...given the drug has been around for more than 50 years, it’s approved, the data on it is well established it’s perplexing that we don’t instruct the use of the drug now with the monitoring of existing coronavirus cases to see the results.

Barry continued the segment by including a response to Jones from Professor Peter Collignon of ANU in which he warns of the drugs toxicity and stresses the need for more trials. He finished with playing the footage of Donald Trump’s comments about injecting disinfectant.

Chris Kenny seems to have taken great offence at the content of this Media Watch segment, despite what is the demonstrably factual content. On The Kenny Report of March 28th he launched an attack at Paul Barry, Media Watch its researchers and funding, and the ABC itself. He spent seven minutes of his time on air to do so claiming the ABC and Paul Barry had a “bizarre new enemy to attack”. Namely hydroxychloroquine.

You can watch The Kenny Report here and access a summary beneath it. Or you can listen to the audio below or grab the mp3 file here (© Sky News).

———————————

In last months post on government cuts to ABC funding I touched on some points that are relevant to this post. Namely the terminology used by Sky News and Chris Kenny to convince viewers that the ABC has a leftist ideology. This is a bold claim and when attacking Media Watch the onus is on Chris Kenny to present not just peer reviewed evidence, but a scientific consensus based on the same to defend climate change denial and now the efficacy of hydroxychloroquine in treating COVID-19.

What is immediately apparent is Kenny’s frequent attacks on ABC funding. In the seven minutes he refers to taxpayer funding of the ABC and Media Watch five times. It’s difficult to imagine even his most devoted fans simply swallowing that. Each time he repeats a version of viewers being presented with “ideological deceit, deceptive tosh, rot, etc”. Kenny begins by telling his audience that Media Watch, “gets a lot wrong – deliberately wrong”. He continues;

One of the most over-resourced shows on television it uses taxpayers money for an ideological platform. It’s supposed to be a media watchdog standing up for truth, accuracy and the like, but what it does is distort the truth and promote inaccuracies in order to promote its own ideological agenda. This breaches the law of course, it breaches the ABC Charter.

This final claim about the ABC Charter is a calculated low blow designed to create significant problems for the ABC which is presently enduring a three year freeze of funding that began in June 2019. This will cost the ABC $83.7 million over the three years. 800 staff have lost their jobs. Yet most significantly as I wrote last month, the ABC has already stressed that the present cuts threaten delivery of the ABC Charter. Yet Kenny contends he is unveiling an “ideological agenda” of Media Watch. Speaking of which, he continues;

Barry and Media Watch preach global warming alarmism, promote leftist climate policies, defend the ABC and attack anyone right of centre. Especially if they work for News Corp – owners of this station. I’ve detailed their deceptions many times before, and I won’t stop.

He goes on to present a “recent example documented in detail by Andrew Bolt”. This is apparently how Media Watch acquitted the ABC over its “obsessive, biased, unfair, relentless and clearly wrong headed persecution of Cardinal George Pell over many years”. He presents an edited clip of Paul Barry speaking on Media Watch. Barry states;

And did the ABC get their judgements on Pell one hundred percent right? Probably not. Was it a witch hunt and a dark day for journalism? I for one do not think so.

Kenny returns with;

How about that for fairness and courage? What a whimp.

The deception employed here by Chris Kenny to create the bogus impression that Paul Barry is biased in favour of the ABC and against George Pell is highly significant. The out-take is from the lengthy Media Watch segment, Pell – The final verdict. When viewed in its entirety we see Barry is critical of ABC identities and programmes when warranted. We also learn that the story of an investigation into Pell was broken by Andrew Bolt’s own paper, the Herald Sun, in February 2016.

Paul Barry also argued against two respected ABC identities that claimed Pell was not “innocent”. Rather it was found there was insufficient evidence to convict. Barry responded to this as follows;

Technically that may be right.

But the principle of our legal system is you’re innocent until proven guilty. And after a unanimous seven-nil verdict from the High Court, you surely can’t argue that Pell is not innocent of the charges.

There are other examples of Barry criticising the ABC. Such as Louise Milligan and Four Corners for not canvassing Pell’s defence, but rather focusing on those who condemned Pell. Or of Barry citing the ABC’s fairness. ABC’s 7:30 did consider if Pell’s conviction was wrong, interviewing Frank Brennan. When Pell’s first appeal was dismissed The Drum had lawyer Richard Beasley appear and he raised concerns that reasonable doubt wasn’t found.

Over the Pell trial and appeals the ABC gave airtime to a large number of Pell supporters. Added to this must go the number of times his supporters turned down an invitation to appear on the ABC. There are many examples of the ABC’s fairness and bipartisanship with respect to Pell. What stands out is Paul Barry’s dedication to applying the same standards to the ABC as to anywhere else. More so in the spirit of Media Watch he has a right to examine if the Pell case was in the public interest and deserving of in depth coverage. Indeed it was, particularly in view of the Royal Commission into Institutional Responses to Child Sexual Abuse. This is what Pell told that Royal Commission;

My own position is that you never disbelieve a complaint. But then it has to be assessed as to see just whether it is valid and true and plausible.

– Revelation, ABC, 2 April, 2020

Thus Chris Kenny’s attack against Paul Barry with respect to Cardinal George Pell and purported ABC bias is without foundation. More so, Kenny has deceived his viewers by using a Media Watch clip out of context. The significance of this rests not least on the accusations of deception Kenny goes on to make against Paul Barry.

Kenny moves on to hydroxychloroquine, claiming the ABC and Paul Barry “don’t like the bloke who speaks positively about it”. Despite the evidence of hydroxychloroquine dangers outlined above, Kenny contends the ABC and Barry are, “actually lining up against drugs that are being trialled around the world. Why? Because the US President hopes they’ll work. I kid you not the left have become that nutty over Donald Trump”.

Kenny contended bias by omission because Paul Barry didn’t include two Australian trials, one of which is currently looking at the prophylactic application of hydroxychloroquine. Kenny made much of the fact he would be speaking to that trial’s lead investigator Professor Marc Pellegrini of the Walter and Eliza Hall Institute of Medical Research in Melbourne. Unfortunately for Chris Kenny it’s not at all clear why ongoing trials support his contention that hydroxychloroquine should be considered safe or that Barry is misleading viewers.

At the time it was known the subjects – all healthcare workers – would be well, fit and rigorously assessed prior to entering the prophylactic trial. To fast forward, recently after the WHO stopped the hydroxychloroquine research of the global Solidarity trial on COVID-19 patients SBS reported that Prof. Pellegrini stated;

The WHO Solidarity trial is worlds apart from what we are doing. Understand that it’s very, very different.

On May 20th Clinical Trials Arena reported;

Pellegrini said: “COVID SHIELD is gold standard in its design as a multi-centre, randomised, double-blind study.

“The trial is focused on our frontline and allied healthcare workers who are at an increased risk of infection due to repeated exposure caring for sick patients. Our aim is to help these people stay safe, well, and able to continue in their vital roles.”

The trial will recruit 2,250 participants who will receive hydroxychloroquine or a placebo tablet over four months.

The other QLD study was part of a national trial looking at both hydroxychloroquine, and lopinavir-ritonavir (a combination treatment used to treat HIV) in the treatment of COVID-19. There were no available results at the time and Paul Barry was not hiding the truth. The focus of his Media Watch segment was media. Not a discussion of various hydroxychloroquine trials.

Well before Kenny went to air the FDA warned of severe heart problems in patients given hydroxychloroquine. Still Kenny attacked Media Watch researchers and bemoaned their funding claiming Barry selectively omits items if they don’t fit “his thesis”.

Kenny worked hard to whip up anger over taxpayer funding of the ABC. He returned to his comment that the real world clinical assessment of hydroxychloroquine was that health professionals were “putting it aside”. This was because he knew that Paul Barry’s “large research team” had received this correspondence from the Pharmaceutical Society of Australia. In it the PSA president notes that there has been an unprecedented demand for hydroxychloroquine following some promising data on the treatment of COVID-19 and Trump’s support of the drug.

It goes on to mention reports from pharmacists that doctors are prescribing for doctors and their families, as are dentists. Non-medical prescribers are prescribing bulk amounts. There is no mention of conclusive data supporting treatment of COVID-19. Key parts of the correspondence include;

If this medication does indeed have the efficacy that we would desire against COVID-19 then it needs to be prescribed and used judiciously. […]

Our strong advice to pharmacists at this point in time, until further advice is available, is to refuse the dispensing of hydroxychloroquine if there is not a genuine need, and that need is for those indications for what it is approved for – inflammatory conditions or the suppression and treatment of malaria. […]

The only way this [treatment of patients who genuinely need the drug] is possible is for prescribers to not write prescriptions for this medicine as a ‘just in case’ measure and for pharmacists to refuse the supply outside of these indications at this point in time.

I’m quite baffled as to why Kenny thinks this letter supports the efficacy of hydroxychloroquine or why he thinks Paul Barry should have included it in his segment. Barry did not accuse Kenny of lying about GPs and dentists grabbing a supply of the drug. Rather, the issue is that Kenny believes such rash behaviour by some health professionals is a “real world clinical assessment of this drug at the moment”. The fact is such off-label prescribing is most certainly not a clinical assessment and to tell viewers this, may have serious, dangerous consequences. TGA amendments to hydroxychloroquine prescription give a clear picture now and did so at the time Kenny went to air.

Kenny was also concerned that Media Watch didn’t mention his interviews with the PSA, Peter Doherty and a number with Professor Peter Collignon of the ANU. This is unusual given what Collignon had said on Alan Jones’ breakfast show on April 9th as reported on the very Media Watch segment Kenny accuses of being selectively and deceptively biased. Collignon stated;

The reality is it’s hard to believe why this drug would work. Now, like all other drugs, I think we’ve got to have an open mind and study them. But there’s as many reports showing it doesn’t work as there are, and it’s not a drug that hasn’t got any toxicity. People have already died from heart conditions by taking this drug in inappropriate dose.

Professor Collignon later told Media Watch by email that larger and more definitive studies were needed and that;

I am even more sceptical as more data is coming in.

Yet Kenny omitted this instead telling his audience;

Paul Barry has deliberately hidden and distorted the truth in order to pretend that we have been misleading you. It’s that brazen, that unhinged and it’s done with your taxpayers money.

Kenny also decided to leave out any mention of Vladimir Zelenko despite him being previously mentioned to support Kenny’s claim of left wing bias against Trump, hence bias against hydroxychloroquine. Zelenko has recently labelled negative data on the drug as “garbage”. Nor did he mention Dr. Anthony Fauci or his position on the drug. He does mention Paul Barry’s reporting of Trump suggesting injection of disinfectant. Kenny then observes;

That’s the level at which Barry operates. Like a kid on Twitter he wants to pretend that the President recommends mainlining Dettol. It’s that inane.

Kenny goes on to disapprove of Barry’s salary which he’s paid, “to produce fifteen minutes of deceptive tosh a week”. He’s not happy that, “up to a dozen researchers” are paid either. Research, Kenny contends, that is, “left out if the facts get in the way of [Barry’s] thesis”. He finishes off with more of the same, this time including a taunt;

The ABC spends, what, two or three million dollars a year on this programme of ideological deceit. And then they scream for more funds – more of your taxes. Good luck with that Ita.

Kenny’s performance is really worth watching. The evidence shows that the one omitting relevant material to deceive his audience is Chris Kenny himself despite his proclamations about Paul Barry. He may have a predetermined, erroneous notion of what Media Watch should be and how it should run. Yet given the many deliberate and malicious references to ABC funding and the motivation of Paul Barry it’s a safe bet that Kenny’s intentions are nefarious. He’s lashing out at Paul Barry and Media Watch because the facts aren’t to his liking or his ideology.

The denial of evidence can always have serious consequences and regarding climate change already has. However at the present time with respect to the COVID-19 pandemic orchestrated deception like that presented by Kenny is not only outrageous, but immoral. The fact is that today so much of right wing rhetoric is anti-science and indeed post truth. That Kenny would cling to his anecdotal belief that the efficacy of hydroxychloroquine can be gleaned from it being snapped up by some health professionals is a failure of critical thinking. That he tried to defend this by tacking together various claims that Paul Barry had omitted material he felt supported his belief gives disturbing insight into the logical fallacies he entertains.

There is really no doubt. Hydroxychloroquine has not been shown to be of genuine benefit in fighting COVID-19 as data stands. Hydroxychloroquine should not be used for COVID-19 outside of clinical trials. Donald Trump was wrong to promote it. Sky News journalists are politically motivated in defending Trump.

Chris Kenny is wrong. He failed to present the evidence. Paul Barry and Media Watch are right. The evidence in this case is what the ABC presented.


UPDATE 6/6/2020: